MicroRNA-194 suppresses prostate cancer migration and invasion by downregulating human nuclear distribution protein.

Human NudC nuclear distribution protein (hNUDC) is differentially expressed between normal and cancer cells. Based on its marked altered expression and its roles in modulating cell division, cytokineses and migration, a detailed understanding of the mechanisms regulating hNUDC expression in cancer cells is critical. In this study, we identified miR-194 as a downstream target of hNUDC and linked its expression to reduced metastatic capacity and tumorigenicity of prostate cancer (PCa) cells.

[Topsoil phosphorus forms and availability of different soil and water conservation plantations in typical black soil region, northeast China].

Aiming to understand soil phosphorus status of plantations in typical black soil region of Northeast China, the topsoil (0-10 cm) phosphorus fractionations and its availability were examined in four soil and water conservation plantations dominantly composed of Larix gmelini, Fraxinus mandshurica, Pinus sylvestris var. mongolica and Populus nigra var. italica x P.

[Surrounding characteristics of preferential flow in cultivated typical black soils of northeast China].

Taking the cultivated soils in typical black soil region of Northeast China as test objects, and by using dye tracer and double-ring infiltrometer techniques and photograph interpretation method, this paper measured and analyzed the dye-stained width and dye-stained coverage of soil transverse and longitudinal sections as well as the field maximum dye-stained depth, aimed to approach the water flow movement pattern and distribution characteristics in test soils. At soil depth 0-15 cm, matrix flow was the main soil water flow movement pattern; at depth 15-20 cm, lateral flow was observed, and the average dye-stained width and dye-stained coverage reached their maximum, being 23 cm and 20.73%, respectively.

[Optimal disposition of water conservation forests in watershed].

Based on the measurements of canopy interception, litter water-holding capacity and soil water storage of different stands in the Erdaoqiao watershed of upper Nenjiang River, the optimal disposition of water conservation forests in this watershed was approached by the method of analytical hierarchy process (AHP). The results showed that in this watershed, the optimal vegetation structure should be 24. 86% of natural birch forest, 16.