Publications by authors named "Xiang-Yin Liu"
Article Synopsis
- The study focuses on a small supernumerary marker chromosome (sSMC) from chromosome 15, analyzing a case involving a 29-year-old woman who underwent amniocentesis due to a potential Down syndrome risk.* -
- Genetic tests revealed that the woman had a chromosomal abnormality, specifically a marker chromosome inherited from her, while the father's chromosomes were normal.* -
- Advanced molecular techniques like fluorescence in situ hybridization (FISH) and chromosomal microarray analysis (CMA) were crucial in identifying the sSMC, aiding in genetic counseling and prenatal diagnostics, and the delivery resulted in a healthy infant.*
Objective: To evaluate the frequency of azoospermia factor (AZFa) microdeletions among infertile men and establish a new high-throughput sequencing method to detect novel deletion types.
Materials And Methods: A total of 3731 infertile men were included. Karyotype analysis was performed using G-band staining of peripheral blood lymphocytes.
Purpose: We investigated the disagreement between the positive cell-free fetal DNA test for trisomy 13 and the standard cytogenetic diagnosis of one case.
Methods: Cell-free fetal DNA testing was performed by massively parallel sequencing. We used conventional cytogenetic analysis to confirm the commercial cell-free fetal DNA testing.
Purpose: To explore the prevalence and clinical features, especially the reproductive function, of 45,X mosaicism patients in northeast China.
Methods: GTG-banding was performed on a series of 2,250 patients from our genetic counseling clinic. Each of these patients underwent a physical examination and was interviewed about their medical history and reproductive problems.