Elevated POSTN expression predicts poor prognosis and is associated with radioresistance in cervical cancer patients treated with radical radiotherapy.

Cervical cancer (CC) is a significant global health issue and remains one of the leading causes of cancer-related mortality in women. Radiotherapy is a crucial treatment modality for CC; however, tumor heterogeneity and resistance to radiotherapy often result in suboptimal outcomes for some patients, including recurrence and metastasis. Periostin (POSTN), a matricellular protein within the tumor microenvironment, has been implicated in the promotion of tumor progression and treatment resistance, particularly through mechanisms such as epithelial-mesenchymal transition (EMT).

[Observation on therapeutic effect of acupuncture intervention combined with hyperbaric oxygen therapy for delayed encephalopathy caused by carbon monoxide poisoning].

Objective: To observe the curative effect of acupuncture intervention combined with hyperbaric oxygen chamber treatment for delayed encephalopathy in 32 carbon monoxide (CO) poisoning patients.

Methods: A total of 62 CO poisoning encephalopathy patients were randomized into control group (n = 30) and acupuncture group (n = 32). Patients of the two groups were all treated with medicines (energy mixture solution, hormones, brain cell activators, calcium ion blockers, anti-inflammatory agents, etc.