Publications by authors named "Xiang-Peng Chen"
Echovirus 18 is a member of the genus Enterovirus, family Picornaviridae, which can cause meningitis in children. Here, we report the echovirus 18 complete genome sequence, which was isolated from the cerebrospinal fluid of a child with aseptic meningitis in Hebei Province, China.
View Article and Find Full Text PDFEpidemics of hand, foot and mouth disease (HFMD) have mainly been caused by Coxsackievirus A16 (CVA16) and Enterovirus A 71 (EV-A71), which circulated alternatively or together in the affected area. CVA16 has caused numerous outbreaks and epidemics in multiple countries and geographical regions, and has become an important public health problem. Based on an analysis of the complete VP1 coding region, all CVA16 strains can be divided into genotypes A, B1, and B2.
View Article and Find Full Text PDFThis study aims to construct inactivated coxsackievirus A16 (CVA16) vaccine and to investigate its protective effect in ICR mice. A clinical isolate of CVA16, 521-01T, was cultured in VERO cells, inactivated by formaldehyde, and purified by ultracentrifugation for vaccine preparation. Purity and other characteristics of the vaccine were determined by SDS-PAGE and Western blot.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated human rhinovirus (HRV) prevalence among children with acute respiratory infections in Gansu Province, collecting 286 throat swabs during 2011.
- Out of these, 27 samples tested positive for HRV, with a notable positive rate of 9.44%, and most affected children were under one year old.
- Genotype analysis revealed HRV A was the predominant strain, making up 84.62% of cases, indicating a variety of HRV genotypes circulated throughout the year, particularly affecting young children.