Transcriptome sequencing and experiments reveal the effect of formyl peptide receptor 2 on liver homeostasis.

Background: Formyl peptide receptor 2 (Fpr2) is an important receptor in host resistance to bacterial infections. In previous studies, we found that the liver of Fpr2 mice is the most severely damaged target organ in bloodstream infections, although the reason for this is unclear.

Aim: To investigate the role of Fpr2 in liver homeostasis and host resistance to bacterial infections.