Publications by authors named "Xiang-Lan Ma"

The purpose of this study was to investigate the efficacy of non-myeloablative allogeneic stem cell transplantation (allo-NST) and its related technologies in hematological malignancies. 26 patients with hematological malignancies (acute leukemia 10, chronic myeloid leukemia 14, multiple myeloma 2) received allo-NST following conditioning regimens with fludarabine/cyclophosphamide/ATG in 14 cases or busulfan or melphalan/cyclophosphamide/ATG in 12 cases prior to infusion of 2 or 3 collections of G-CSF (600 microg/d) or G-CSF (300 microg/d) plus GM-CSF (300 microg/d) mobilized blood stem cell on the fifth day. A combination of cyclosporine A (CsA) and methotrexate (MTX) was administered for GVHD prophylaxis.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers tested a type of stem cell treatment called non-myeloablative allogeneic stem cell transplantation (allo-NST) on 26 patients with blood cancers.
  • Most patients (84.62%) successfully accepted the transplant, and only a few experienced serious side effects like graft-versus-host disease (GVHD).
  • The study suggests that allo-NST is a safe and effective way to treat these cancers, but more research is needed on the treatment details.
View Article and Find Full Text PDF