Publications by authors named "Xiang-Fen Hao"
Article Synopsis
- Cynomolgus monkeys were used to create disease models mimicking the early stages of type 2 diabetes by feeding them various high-energy diets.
- Researchers monitored the monkeys' health through metabolic characteristics and glucose tolerance tests, analyzing the expression of 45 diabetes-related genes.
- The study found significant gene expression changes across different diet groups, suggesting that these animals can serve as a reference for understanding early diagnostics and the causes of type 2 diabetes in humans.*
The correlation between cardiovascular risk factors and cardiovascular disease related genes plays an important role in early-warning risk and early diagnosis. Thirty middle-aged male crab-eating macaques were fed a moderately atherogenic diet (0.053 mg cholesterol/kJ and 40% of calories as saturated fat) for twelve months.
View Article and Find Full Text PDFType 2 diabetes mellitus (T2DM) is a metabolic disease with a strong genetic component that is very prevalent in the world. The aim of this study is to investigate the association of a set of six obesity-related genes with the different disease phases of T2DM in a model using middle or aged cynomogus monkeys. A total of 25 male monkeys were used and fed with high-fat diet (15% lard).
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