Depression and anxiety, peripheral blood inflammatory factors, and stress levels on therapeutic outcomes in patients with chronic wounds.

Background: The incidence of chronic wounds is rising due to an aging population and lifestyle changes in our country. In addition, as the disease spectrum evolves, chronic wounds have become common clinical issues that seriously threaten health and impose significant social and economic burdens.

Aim: To investigate how depression, anxiety, peripheral blood inflammatory factors, and stress levels affect therapeutic outcomes in patients with chronic wounds.

Food web bioaccumulation model for ecological risk assessment of emerging organic pollutants in marine ecosystems: Principles, advances and challenges.

The bioaccumulation and trophic transfer of pollutants in marine ecosystem members determine their ultimate ecological risks. Food web bioaccumulation models are widely used in scientific and regulatory programs to assess the bioaccumulation and ecological risks of pollutants at the ecosystem scale. The food web models are mainly established through concentration- and fugacity-based modeling approaches and include some chemical, food web-related, physiological and environmental factors.

Unveiling spatiotemporal distribution, partitioning, and transport mechanisms of tire additives and their transformation products in a highly urbanized estuarine region.

Numerous tire additives are high-production volume chemicals that are used extensively worldwide. However, their presence and partitioning behavior remain largely unknown, particularly in marine environments. This study is the first to reveal the spatiotemporal distribution, multimedia partitioning, and transport processing of 22 tire additives and their transformation products (TATPs) in a highly urbanized estuary (n = 166).

Unraveling the toxicity mechanisms of nanoplastics with various surface modifications on Skeletonema costatum: Cellular and molecular perspectives.

Nanoplastics are ubiquitous in marine environments, exhibiting high bioavailability and potential toxicity to marine organisms. However, the impacts of nanoplastics with various surface modifications on marine microalgae remain largely unexplored. This study explored the toxicity mechanisms of two nanoplastic types-polystyrene (PS) and polymethyl methacrylate (PMMA)-with distinct surface modifications on Skeletonema costatum at cellular and molecular levels.

Fate and drivers of mariculture-derived microplastics from ponds to mangrove forests.

Due to the combined influences of marine and terrestrial disturbances, the sources of microplastics (MPs) in mangrove ecosystems are complex and diverse. Previous studies have inferred the possible involvement of mariculture activities as a potential source of mangrove MPs based on the characteristics of MPs. However, the direct contributions of mariculture-derived MPs to mangrove MPs remain largely unknown.

First Evidence of the Bioaccumulation and Trophic Transfer of Tire Additives and Their Transformation Products in an Estuarine Food Web.

The discovery of the significant lethal impacts of the tire additive transformation product -(1,3-dimethylbutyl)-'-phenyl--phenylenediamine quinone (6PPD-Q) on coho salmon has garnered global attention. However, the bioaccumulation and trophic transfer of tire additives and their transformation products (TATPs) within food webs remain obscure. This study first characterized the levels and compositions of 15 TATPs in the Pearl River Estuary, estimated their bioaccumulation and trophic transfer potential in 21 estuarine species, and identified priority contaminants.

Organophosphate flame retardants and their metabolites in the Pearl River Estuary: Occurrence, influencing factors, and ecological risk control strategies based on a mass balance model.

Estuaries serve as crucial filters for land-based pollutants to the open sea, but there is a lack of information on the migration and fate of organophosphate flame retardants (OPFRs) within estuaries. This study focused on the Pearl River Estuary (PRE) by examining the co-occurrence of OPFRs and their metabolites and quantifying their transport fluxes using a mass balance model. The seawater concentrations of OPFRs and their metabolites exhibited significant seasonal variations (p < 0.

Intraperitoneal hyaline vascular Castleman disease: Three case reports.

Background: Castleman disease (CD) was first reported in 1954. It is a rare non-malignant lymphoproliferative disease with unclear etiology. As the clinical manifestations of CD are different, there are difficulties in its diagnosis and treatment.

First insights into the bioaccumulation, biotransformation and trophic transfer of typical tetrabromobisphenol A (TBBPA) analogues along a simulated aquatic food chain.

Tetrabromobisphenol A (TBBPA) analogues have been investigated for their prevalent occurrence in environments and potential hazardous effects to humans and wildlife; however, there is still limited knowledge regarding their toxicokinetics and trophic transfer in aquatic food chains. Using a developed toxicokinetic model framework, we quantified the bioaccumulation, biotransformation and trophic transfer of tetrabromobisphenol S (TBBPS) and tetrabromobisphenol A di(allyl ether) (TBBPA-DAE) during trophic transfer from brine shrimp (Artemia salina) to zebrafish (Danio rerio). The results showed that the two TBBPA analogues could be readily accumulated by brine shrimp, and the estimated bioconcentration factor (BCF) value of TBBPS (5.

[Association of maternal isolated thyroid peroxidase antibody positive in the first trimester with fetal growth].

Objective: To investigate the association of isolated thyroid peroxidase antibody (TPOAb) positive in the first trimester with fetal growth.

Methods: A total of 16 446 pregnant women were included in the birth cohort study, whose last menstrual period was between May 2016 and April 2019 and with singleton pregnancy. Maternal serum samples were collected when they firstly came for prenatal care in the first trimester.

Steroid metabolites as overlooked emerging contaminants: Insights from multimedia partitioning and source-sink simulation in an estuarine environment.

Steroids have been attracting global attention given potential carcinogenic and endocrine-disrupting effects, yet the environmental status of steroids, especially their metabolites, in estuarine environment remain largely unexplored. This study investigated 31 steroids and metabolites in suspended particulate matter (SPM), water phase and sediments of the Pearl River Estuary (PRE) during the dry and wet seasons to elucidate their spatiotemporal patterning, partitioning behavior, and environmental fate. The results showed that natural steroids predominated in SPM and sediments while the metabolites predominated in water.

Vertical distribution and transport of microplastics in the urban atmosphere: New insights from field observations.

The distribution and transport of atmospheric microplastics (AMPs) have raised concerns regarding their potential effects on the environment and human health. Although previous studies have reported the presence of AMPs at ground level, there is a lack of comprehensive understanding of their vertical distribution in urban environments. To gain insight into the vertical profile of AMPs, field observations were conducted at four different heights (ground level, 118 m, 168 m and 488 m) of the Canton Tower in Guangzhou, China.

Free and conjugated forms of metabolites are indispensable components of steroids: The first evidence from an estuarine food web.

Steroids have attracted particular attention as environmental contaminants because of their severe endocrine-disrupting effects. Previous studies have predominantly focused on parent steroids; however, the levels and proportions of the free and conjugated forms of their metabolites remain largely unclear, especially in food webs. Here, we first characterized the free and conjugated forms of parent steroids and their metabolites in 26 species in an estuarine food web.

An effective tool for tracking steroids and their metabolites at the watershed level: Combining fugacity modeling and a chemical indicator.

Steroids have attracted concern worldwide because of their potential carcinogenicity and severe adverse effects on aquatic organisms. However, the contamination status of various steroids, particularly their metabolites, at the watershed level remains unknown. This was the first study to employ field investigations to elucidate the spatiotemporal patterns, riverine fluxes, and mass inventories, and conduct a risk assessment of 22 steroids and their metabolites.

Adsorption of heavy metals on biodegradable and conventional microplastics in the Pearl River Estuary, China.

In recent years, microplastics (MPs) as emerging carriers for environmental pollutants have attracted increasing worldwide attention. However, the adsorption of heavy metals on MPs, especially for biodegradable MPs, has been still poorly understood in estuarine environments. In this study, we investigated the aging of biodegradable and conventional MPs in the Pearl River Estuary after long-term exposure and their impacts on the adsorption of heavy metals from seawater.

Expanded polystyrene buoys as an important source of hexabromocyclododecanes for aquatic ecosystem: Evidence from field exposure with different substrates.

The production and use of hexabromocyclododecanes (HBCDs) have been strictly limited due to their persistence, toxicity and bioaccumulation. However, the release of HBCDs from related products and wastes would continue for a long time, which may cause many environmental problems. In this study, we investigated the occurrence and distribution of HBCDs and microplastics (MPs) in aquatic organisms inhabiting different substrates.

Microplastics contamination in bivalves from the Daya Bay: Species variability and spatio-temporal distribution and human health risks.

Microplastic contamination is an emerging global threat for various marine organisms. Marine invertebrates such as bivalve mollusks are more susceptible to the widespread presence of microplastics due to their limited abilities to escape from pollution exposure and they can readily ingest environmental pollutants like microplastics through their filter-feeding behaviors. In this study, microplastic contamination in bivalves related to species, spatial, and temporal variability were conducted.

The relationship between online courses and mental health among Chinese children.

Background: Previous studies on the association of online courses and mental health were mainly conducted in universities, and no study investigated the relationship between characteristics of online courses and children's mental health in primary and secondary school. This study aimed to explore the association of online courses and children's mental health in primary and secondary school.

Methods: A cross-sectional study was conducted through an online survey among 540 primary and secondary school students and their parents in the eastern, central and western region of China from April to May in 2020.

Tetrabromobisphenol A and hexabromocyclododecanes in sediments from fishing ports along the coast of South China: Occurrence, distribution and ecological risk.

Tetrabromobisphenol A (TBBPA) and hexabromocyclododecanes (HBCDDs) have attracted extensive attention due to their strong persistence and toxicity. However, little has been known about their pollution status in fishing ports, which are typical sinks of land-sourced pollutants. In this study, we investigated the occurrence, distribution and ecological risk of TBBPA and HBCDDs in sediments from fishing ports along the coast of South China.

Microplastic contamination in marine-cultured fish from the Pearl River Estuary, South China.

Microplastics are ubiquitous in the aquatic environment. However, the occurrence of microplastics in farmed fish is under-researched. Herein, microplastic abundance in the stomach and intestine of marine-cultured hybrid groupers (Epinephelus fuscoguttatus × Epinephelus lanceolatus) in the Pearl River Estuary (PRE) was examined.

Microplastic pollution in the surface seawater in Zhongsha Atoll, South China Sea.

The prevalence of microplastics in the marine environment has attracted extensive attention. So far, no information is known regarding the temporal and spatial variations of microplastics in Zhongsha Atoll. This study, for the first time, comprehensively investigated the occurrence and distribution of microplastics in the surface seawater in Zhongsha Atoll based on two ocean cruises.

Contamination and ecological risks of steroid metabolites require more attention in the environment: Evidence from the fishing ports.

Due to strong endocrine disrupting effects, steroids in the environment have attracted substantial attention, with studies mostly focusing on the parent steroids. Here, we conducted the first investigation on the contamination profiles, possible sources, mass inventories, and ecological risks of 27 steroids and their metabolites in 15 typical fishing ports in Southeast China. Twelve steroids were detectable in the sediment samples with the total mean concentrations of 4.

Characteristics of expanded polystyrene microplastics on island beaches in the Pearl River Estuary: abundance, size, surface texture and their metals-carrying capacity.

While expanded polystyrene (EPS) microplastics have been widely recognized as one of the most important components of plastic litter in the intertidal zones of the global ocean, our understanding of their environmental fate on island beaches is insufficient. In this study, we intended to reveal that the latest EPS microplastic pollution status on 5 island beaches in the Pearl River Estuary, China, by comprehensively assessing the abundance, distribution, size, surface texture and carrying capacity of heavy metals (Cd, As, Cr, Ni, Cu, Pb, Mn, Fe, Al). High level of EPS microplastic abundance ranged from 328 to 82,276 particles m was found, with the highest abundance at Guishan Island and the lowest at Dong'ao Island.