Long-term exposure to ozone and sleep disorders in children: A multicity study in China.

Evidence regarding the link between long-term ambient ozone (O) exposure and childhood sleep disorders is little. This study aims to examine the associations between long-term exposure to O and sleep disorders in children. We conducted a population-based cross-sectional survey, including 185,428 children aged 6-18 years in 173 schools across 14 Chinese cities during 2012 and 2018.

Associations of short-term changes in obesity indices with all-cause mortality and cardiovascular disease.

Objective: This study aimed to investigate how short-term changes (1-, 3-, and 5-year) in obesity measures affect mortality and cardiovascular disease (CVD) risk.

Methods: We analyzed longitudinal data from the MJ Health Centre (n = 43,304 for the 1-year study; 24,295 for the 3-year study; 16,138 for the 5-year study) with median follow-up periods of 15.8, 13.

The Association between Bone Mineral Density and Risk of Mortality: A Prospective Cohort Study of 233,397 Taiwanese.

Purpose: Osteoporosis is an important public health challenge given its high prevalence in western populations and the prevalence has shown an upward trend in recent decades in Asia. However, epidemiological evidence on the association between bone mineral density (BMD) and mortality risk in the Asian population is sparse.

Methods: The Cox proportional hazards model and cause-specific hazard models were used to investigate the association of BMD with the risk of all-cause mortality and cause-specific mortality.

Effect of environmental exposome and influenza infection on febrile seizure in children over 22 years: a time series analysis.

Febrile seizures are convulsions predominately occurring in young children. The effects of various exposomes, including influenza infection and external environmental factors, on febrile seizures have not been well-studied. In this study, we elucidated the relationships between ambient temperature, air pollutants, influenza infection, and febrile seizures using 22-year territory-wide hospitalization data in Hong Kong.

Environmental pollution to kidney disease: an updated review of current knowledge and future directions.

Environmental pollution significantly impacts global disease burden. However, the contribution of environmental pollution to kidney disease is often overlooked in nephrology. This review examines the growing body of research demonstrating the significant impacts of environmental pollutants, with a focus on air pollution as a primary factor, and acknowledges the roles of other pollutants, such as heavy metals, in the development and progression of kidney diseases.

The joint effect of long-term exposure to multiple air pollutants on non-accidental and cause-specific mortality: A longitudinal cohort study.

The long-term joint impacts of fine particulate matter (PM), nitrogen dioxide (NO), and ozone (O) on mortality are inconclusive. To bridge this research gap, we included 283,568 adults from the Taiwan MJ cohort between 2005 and 2016 and linked with the mortality data until 31 May 2019. Participants' annual average exposures to PM, NO, and O were estimated using satellite-based spatial-temporal models.

Chronic exposure to ambient air pollution and the risk of non-alcoholic fatty liver disease: A cross-sectional study in Taiwan and Hong Kong.

Background: Information on the relation of air pollution with non-alcoholic fatty liver disease (NAFLD) is scarce. We thus conducted a large cross-sectional study in Asia to investigate the role of air pollution in NAFLD.

Methods: We recruited 329,048 adults (mean age: 41.

Exposure to Neighborhood Greenness and Hypertension Incidence in Adults: A Longitudinal Cohort Study in Taiwan.

Background: There are few studies on the health effects of long-term exposure to neighborhood greenness in a longitudinal setting, especially in Asian countries with high population densities.

Objectives: This study investigates the association between long-term exposure to neighborhood greenness and hypertension among adults in Taiwan.

Methods: We selected 125,537 participants ( of age) without hypertension from Taiwan who had joined the standard medical examination program between 2001 and 2016.

Trajectories of body mass index before the diagnosis of type 2 diabetes in a cohort of Taiwanese adults.

Background: Although the prevalence of overweight/obesity is lower in Asian countries, the risk of type 2 diabetes (T2DM) is disproportionally higher. We identified and characterized the trajectory patterns of body mass index (BMI) before the onset of T2DM in a Taiwanese population.

Methods: Using the Taiwan MJ cohort study, we sampled the health examination data of 22,934 participants, including 7618 cases of T2DM and 15,316 controls.

Outdoor artificial light at night and incident cardiovascular disease in adults: A national cohort study across China.

Cardiovascular diseases (CVDs) become a major public health concern. Evidence concerning the effects of outdoor artificial light at night (ALAN) on CVD in adults is scarce. We aimed to investigate the extent to which outdoor ALAN could affect the risk of CVD over a exposure range.

Outdoor light at night and mortality in the UK Biobank: a prospective cohort study.

Background: More than 83% of the world's population lives under light-polluted skies while information about health effects of outdoor light at night (LAN) is limited. We examined the association of LAN with natural cause (NC) and cardiovascular disease (CVD) mortality using the UK Biobank.

Methods: We included 273 335 participants recruited between 2006 and 2010.

Net effect of air pollution controls on health risk in the Beijing-Tianjin-Hebei region during the 2022 winter Olympics and Paralympics.

Due to the non-linearity in ozone (O) formation, reducing the emission of nitrogen oxides (NO) may increase O concentration. Given the counteractive O response to NO reduction, overall impact of air pollution controls can be ambiguous when the assessments focus on the changes in pollutant concentrations. In this study, a risk-based method was used to gauge the net effect of air pollution controls on mortality risk in the Beijing-Tianjin-Hebei (BTH) region during the 2022 Winter Olympics and Paralympics (WOP).

Spatiotemporal Trends of Stroke Burden Attributable to Ambient PM in 204 Countries and Territories, 1990-2019: A Global Analysis.

Background And Objectives: Previous studies suggested that long-term exposure to ambient fine particulate matter (PM) is associated with increased risk of stroke. However, limited studies evaluated the stroke burden attributable to ambient PM globally, especially comprising across different regions, countries, and social-economic levels. We thus conducted this study to estimate the spatial and temporal trends of ambient PM-related stroke burden by sex, age, and subtypes from 1990 to 2019 at global, regional, and national levels.

Chronic exposure to ambient PM/NO and respiratory health in school children: A prospective cohort study in Hong Kong.

Despite increasing concerns about the detrimental effects of air pollution on respiratory health, limited evidence is available on these effects in the Hong Kong population, especially in children. In this prospective cohort study between 2012 and 2017, we aimed to investigate the associations between exposure to air pollution (concentrations of fine particulate matter [PM] and nitrogen dioxide [NO]) and respiratory health (lung function parameters and respiratory diseases and symptoms) in schoolchildren. We recruited 5612 schoolchildren aged 6-16 years in Hong Kong.

Isolated systolic or diastolic hypertension and mortality risk in young adults using the 2017 American College of Cardiology/American Heart Association blood pressure guideline: a longitudinal cohort study.

Background: Little is known regarding the health effects of different hypertension phenotypes including isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH), and systolic and diastolic hypertension (SDH) defined by the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guideline among young adults. We conducted this longitudinal study using time-varying analyses to evaluate the relationship between cardiovascular/all-natural mortality risk and different hypertension phenotypes in young adults.

Methods: A total of 284 597 young adults (aged 18-39 years) were recruited between 1996 and 2016.

Relationship between meteorological variations, seasonal influenza, and hip fractures in the elderly: A modelling investigation using 22-year data.

With the heavy negative health effect and economic burden of hip fractures in the elderly, the relationship of hip fractures with climate and seasonal influenza has not been quantified explicitly. In this study, we aim to make use of population-based data to evaluate the impact of meteorological factors and influenza activity on the hip fracture admissions for the elderly in Hong Kong from 1998 to 2019. Weekly numbers of admissions for the elderly due to hip fractures were used as the study outcome, and were matched with the meteorological factors included air temperature, relative humidity, solar radiation, and total rainfall.

Associations between long-term exposure to multiple air pollutants and age at menopause: a longitudinal cohort study.

Background: To investigate the associations between long-term exposure to ambient air pollution and age at menopause and the risk of early menopause in two Asian cohorts.

Methods: A total of 53,167 female adults were enrolled from two ongoing cohorts, one each in Taiwan and Hong Kong, between 2003 and 2018, yielding 200,000 person-years of follow-up. We performed a Cox regression model with time-dependent covariates to investigate associations between air pollution and menopause.

Cardiovascular Mortality, Habitual Exercise, and Particulate Matter 2.5 Exposure: A Longitudinal Cohort Study.

Introduction: Habitual exercise may amplify the respiratory uptake of air pollutants in the lung, exacerbating the adverse effects of air pollution. However, it is unclear whether this can reduce the health benefits of habitual exercise (referred to as leisure-time exercise). Thus, the combined effects of habitual exercise and chronic exposure to ambient fine particulate matter 2.

Novel lipid indicators and the risk of type 2 diabetes mellitus among Chinese hypertensive patients: findings from the Guangzhou Heart Study.

Background: Data are limited on whether several easily measured indices are independent predictors of type 2 diabetes mellitus (T2DM) in hypertensive patients. This study aimed to assess the association of hypertriglyceridemic-waist phenotype, triglyceride glucose (TyG) index, lipid accumulation product (LAP), and visceral adiposity index (VAI) with T2DM risk in hypertensive patients.

Methods: This cross-sectional study included 5321 hypertensive patients from the baseline survey of the Guangzhou Heart Study.

Risk tradeoffs between nitrogen dioxide and ozone pollution during the COVID-19 lockdowns in the Greater Bay area of China.

Photochemical regime for ozone (O) formation is complicated in the sense that reducing emission of nitrogen oxides (NO) may increase O concentration. The lockdown due to COVID-19 pandemic affords a unique opportunity to use real observations to explore the O formation regime and the effectiveness of NO emission control strategies. In this study, observations from ground networks during the lockdowns were used to assess spatial disparity of the Ratio of Ozone Formation (ROF) for nitrogen dioxide (NO) reduction in the Greater Bay Area (GBA) of China.

Multi-pollutant air pollution and renal health in Asian children and adolescents: An 18-year longitudinal study.

Background: Few studies have examined the effects of multi-pollutant air pollution on renal health, especially in children and adolescents. This study investigated the association between long-term ambient air pollution exposure and renal health in Asian children and adolescents.

Methods: This study included 10,942 children and adolescents from Taiwan and Hong Kong between 2000 and 2017.

Life-course exposure to ambient fine particulate matter and hypertension in adulthood: a longitudinal cohort study.

PM-hypertension association were well documented in adults, while the effects of life-course exposure to PM on adulthood hypertension remained unclear. This study aimed to investigate the associations between life-course exposure to ambient PM and incident hypertension in adulthood in Asia. We included 4272 participants with 17,814 medical visits from two open cohorts in Taiwan and Hong Kong between 2000 and 2018.

Habitual Exercise, Air Pollution, and Pneumonia Mortality: A Longitudinal Cohort Study of Approximately 0.4 Million Adults.

In this study, we aimed to examine the combined associations of particulate matter with an aerodynamic diameter less than or equal to 2.5 μm (PM2.5) and habitual exercise with pneumonia mortality.

Habitual exercise, chronic exposure to fine particulate matter and high-sensitivity C reactive protein in Asian adults.

Objectives: Exercise may increase the inhaled amount of air pollutants and exacerbate the adverse health effects. We investigated the combined effects of chronic exposure to fine particulate matter with an aerodynamic diameter less than 2.5 µm (PM) and habitual exercise on C reactive protein (CRP), a sensitive marker of inflammation.