J Environ Manage
January 2025
Transparent Exopolymer Particles (TEP), closely related to the carbon cycle due to their high carbon-to-nitrogen ratio, have become a hot research topic. However, despite the growing interest in this field, there is a lack of comprehensive analysis providing a clear developmental background and quantitative research on the overall trends of TEP studies. To address the gap, this article utilizes VOSviewer and CiteSpace to conduct a bibliometric analysis of TEP research.
View Article and Find Full Text PDFThe use of immobilized microbial technology in wastewater treatment has drawn extensive attention due to its advantages of high colony density, rapid reaction speed, and good stability. Immobilization carriers are the core of immobilization technology. This review summarizes the types of immobilization carriers and their advantages and disadvantages, focusing on the potential for utilizing novel immobilization carriers (composite carriers, nanomaterials, metal-organic frameworks (MOFs), and biochar materials) in wastewater applications.
View Article and Find Full Text PDFObjectives: To address the nursing crisis, it is imperative to comprehend the factors that influence nursing competencies, which are crucial for the delivery of quality patient care.
Background: Facing demographic shifts and increasingly complex healthcare demands, China's nursing sector struggles with workforce shortages and the need to enhance core competencies. This research explores the interplay of social support, psychological resilience, mindfulness and nursing competencies in various hospital environments in China.
Osteoarthritis (OA) is a chronic degenerative disease characterized by overall joint tissue damage. Metformin (Met) has been shown to inhibit inflammatory reactions, though its potential protective mechanism on cartilage remains unclear. This study investigated Met's potential to protect cartilage in an OA rat model.
View Article and Find Full Text PDFStretchable electronics have demonstrated excellent potential in wearable healthcare and conformal integration. Achieving the scalable fabrication of stretchable devices with high functional density is the cornerstone to enable the practical applications of stretchable electronics. Here, a comprehensive methodology for realizing large-scale, 3D, and stretchable circuits (3D-LSC) is reported.
View Article and Find Full Text PDFBecause traditional lithium-ion batteries have been unable to meet the energy density requirements of various emerging fields, lithium-metal batteries (LMBs), known for their high energy density, are considered promising next-generation energy storage batteries. However, a series of problems, including low coulombic efficiency and low safety caused by dendrites, limit the application of lithium metal batteries. Herein, fluoro-oxygen codoped graphene (FGO) was used to modify the copper current collector (FGO@Cu).
View Article and Find Full Text PDFSilk fibroin (SF) has excellent biocompatibility and is one of the most commonly used polymer materials. However, SF fibers have serious drawbacks as antibacterial materials due to their lack of stability and bacterial resistance. Therefore, it is of paramount significance to enhance the stability and bolster the bacterial resistance of SF fibers.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2024
Sarcopenia and diabetes are two age-related diseases that are common in the elderly population, and have a serious effect on their general health and quality of life. Sarcopenia refers to the progressive loss of muscle mass, strength and function, whereas diabetes is a chronic disease characterized by elevated blood sugar levels. The comorbidity of sarcopenia and diabetes is particularly concerning, as people with diabetes have a higher risk of developing sarcopenia due to the combination of insulin resistance, chronic inflammation and reduced physical activity.
View Article and Find Full Text PDFGenistein (GN) has been highly recommended for its medicinal properties like anticancer, antidiabetic, antihyperlipidemic, antiviral, and antioxidant activities among others. Recently, scientists realized that Genistein is an endocrine disruptor. It is an obesogen that interferes with the endocrine system causing obesity through many mechanisms like inducing adipocyte differentiation, lipid accumulation, and transformation of some stem cells into adipocytes (bone marrow mesenchymal stem cells for example) .
View Article and Find Full Text PDFAims: The use of non-steroid anti-inflammatory drugs (NSAIDs) is conventional in management of postoperative pain in cancer patients, and further investigations have reported that some of these drugs correlated with the outcome in cancers. However, the prognostic value of the use of NSAIDs during surgery in non-small cell lung cancer (NSCLC) patients has been less addressed.
Methods: NSCLC patients staged I-III are retrospectively enrolled, and the data of the use of NSAIDs during surgery are collected.
Bioflavonoids are natural polyphenolic secondary metabolites that are medicinal. These compounds possess antitumor, cardioprotective, anti-inflammatory, antimicrobial, antiviral, and anti-psoriasis properties to mention a few. Plant species that contain bioflavonoids should be preserved as such.
View Article and Find Full Text PDFMaillard reaction in pharmaceutical preparations refers to a complex chemical reaction existing between reducing excipients and amino-containing drugs in preparations, which can cause a series of quality problems in preparations. Maillard reaction belongs to chemical incompatibility in preparations, and measures should be taken to reduce or avoid it. In this study, the effect of cyclodextrins (commonly used pharmaceutical excipients) on the Maillard reaction and its mechanism in the lysine hydrochloride-lactose solid preparation model were explored for the first time.
View Article and Find Full Text PDFNatural ingredients have many applications in modern medicine and pharmaceutical projects. However, they often have low solubility, poor chemical stability, and low bioavailability . Spray drying technology can overcome these challenges by enhancing the properties of natural ingredients.
View Article and Find Full Text PDFBackground: Forest aboveground biomass (AGB) is not only the basis for estimating forest carbon storage, but also an important parameter for evaluating forest carbon cycle contribution and forest ecological function. Data saturation and fewer field plots limit the accuracy of AGB estimation. In response to these questions, we constructed a point-line-polygon framework for regional coniferous forests AGB mapping using field survey data, UAV-LiDAR strip data, Sentinel-1 and Sentinel-2 imageries in this study.
View Article and Find Full Text PDFAutonomous driving is an important branch of artificial intelligence, and real-time and accurate object detection is key to ensuring the safe and stable operation of autonomous vehicles. To this end, this paper proposes a fast and accurate object detector for autonomous driving based on improved YOLOv5. First, the YOLOv5 algorithm is improved by using structural re-parameterization (Rep), enhancing the accuracy and speed of the model through training-inference decoupling.
View Article and Find Full Text PDFThe ability to not only control but also maintain the well-defined size of nanoclusters is key to a scientific understanding as well as their practical application. Here, we report a synthetic protocol to prepare and stabilize nanoclusters of different metals and even metal salts. The approach builds on a Pickering stabilization effect inside a microemulsion system.
View Article and Find Full Text PDFAims: Hematological markers that can be used for prognosis prediction for stage I lung adenocarcinoma (LUAD) are still lacking. Here, we examined the prognostic value of a combination of the red cell distribution width (RDW) and carcinoembryonic antigen (CEA), namely, the RDW-CEA score (RCS), in stage I LUAD.
Materials And Methods: A retrospective study with 154 patients with stage I LUAD was conducted.
Background: The prognostic nutritional index (PNI) and D-dimer (DD) levels represent useful prognostic indicators in colorectal cancer (CRC); however, a combination of these indicators, namely, the PNI and DD score (PDS) was less addressed.
Methods: A retrospective study with 183 patients after curative surgery was conducted. Patients were divided into 3 subgroups: PDS 0, decreased PNI and increased DD levels; PDS 1, decreased or increased PNI and DD levels; PDS 2, increased PNI and decreased DD levels.
Both carcinoembryonic antigen (CEA) level and body mass index (BMI) are traditional prognostic markers in colorectal cancer (CRC); however, to the best of our knowledge, the value of the CEA to BMI ratio (CBR) has never been addressed. In the present study, 191 patients with CRC treated using radical resection were retrospectively included, and the significance of the CBR in predicting disease-free survival (DFS) or overall survival (OS) rates was calculated. The prognostic efficacy of the CBR in predicting OS was compared with individual CEA and BMI values.
View Article and Find Full Text PDFBackground: Preoperative absolute lymphocyte count (ALC) and carcinoembryonic antigen (CEA) are useful prognostic indicators in colorectal cancer (CRC); however, the role of the ALC-to-CEA ratio (LCR) has been less addressed.
Methods: A total of 189 stage I to III CRC patients who underwent radical resection were enrolled retrospectively. The significance of the LCR in predicting disease-free survival (DFS) and overall survival (OS) was calculated and compared with other markers based on ALC.
Aims: Adjuvant chemotherapy (ACT) plays an important role in improving the survival of stage II-III colorectal cancer (CRC) patients after curative surgery. However, the prognostic role of irregular delay of ACT (IDacT) for these patients has been less studied.
Materials And Methods: A total of 117 stage II-III CRC patients who underwent radical resection and received at least 3 months ACT were enrolled retrospectively.
Background: The prognostic value of intratumor T regulatory cells (Tregs) in colorectal cancer (CRC) was previously reported, but the role of these cells in tumor draining lymph nodes (TDLNs) was less addressed.
Methods: A total of 150 CRC stages I-IV were retrospectively enrolled. Intratumor and TDLN Tregs were examined by immunohistochemical assay.
Antifreeze proteins (AFPs) or thermal hysteresis (TH) proteins are biomolecular gifts of nature to sustain life in extremely cold environments. This family of peptides, glycopeptides and proteins produced by diverse organisms including bacteria, yeast, insects and fish act by non-colligatively depressing the freezing temperature of the water below its melting point in a process termed thermal hysteresis which is then responsible for ice crystal equilibrium and inhibition of ice recrystallisation; the major cause of cell dehydration, membrane rupture and subsequent cryodamage. Scientists on the other hand have been exploring various substances as cryoprotectants.
View Article and Find Full Text PDFPreoperative serum albumin (ALB) and carcinoembryonic antigen (CEA) were useful prognostic factors in colorectal cancer (CRC); however, the ALB to CEA ratio (ACR) and their individual prognostic efficacies have been less studied. A retrospective study with 156 CRC patients staged I to IV was performed. The prognostic efficacy of ACR was estimated and subsequently compared with ALB, CEA, and other systemic inflammation markers, including the neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), and platelet-to-lymphocyte ratio (PLR).
View Article and Find Full Text PDFClinically, the effective treatment for patients with acute ischemic stroke (AIS) is very limited. Therefore, this paper aims to investigate the mechanism how astragalus polysaccharide (APS) exerts protective effect against AIS and provide a new method for the treatment of AIS. Cell surface antigen flow cytometry and immunofluorescence were used to identify M1 and M2 microglia.
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