Publications by authors named "Xianchao Yu"
Article Synopsis
- Nutcracker syndrome is a complex disease that causes various symptoms and is often difficult to diagnose, leading to a challenging experience for patients.
- The study focused on understanding how blood flow and pressure changes in the left renal vein relate to this syndrome by simulating different levels of vein compression using 3D vascular models.
- Results showed that more severe compression leads to distinct patterns in blood flow and pressure, which could help in diagnosing and understanding the underlying mechanisms of nutcracker syndrome.
Tumor-infiltrating immune cells (TICs) affect tumorigenesis and tumor development in head and neck squamous cell carcinoma (HNSCC). We constructed a novel predictive model for HNSCC based on immune-related genes (IRGs) from The Cancer Genome Atlas and the Immunology Database and Analysis Portal. After identifying the IRGs, a predictive model involving 13 IRGs with high stratification value of overall survival (OS) was constructed by multiple support vector machine recursive feature elimination and least absolute shrinkage and selection operator regression.
View Article and Find Full Text PDFBackground And Objectives: Real-time blood flow variation is crucial for understanding the dynamic development of coronary atherosclerosis. The main objective of this study is to investigate the effect of varying extent of stenosis on the hemodynamic features in left anterior descending coronary artery.
Methods: Various Computational fluid dynamics (CFD) models were constructed with patient-specific CT image data, using actual fractional flow reserve (FFR) as boundary conditions to provide a real-time quantitative description of hemodynamic properties.
Surface tension (σ) isotherms of liquid mixtures can be divided into Langmuir-type (L-type, including L- and L-type) and sigmoid-type (S-type, including S- and S-type). Many models have been developed to describe the σ-isotherms. However, the existing models can well describe the L-type isotherms, but not the S-type ones.
View Article and Find Full Text PDFPurpose: To investigate the different imaging features of contrast-enhanced multidetector-row-computed tomography (MDCT) for distinguishing between silicosis and tuberculosis involving the mediastinal lymph nodes.
Methods: 86 silicosis patients and 61 tuberculosis patients with mediastinal lymphadenopathy based on contrast-enhanced MDCT were included. The enhanced patterns, anatomical distribution and calcification features of the enlarged lymph nodes were retrospectively compared between the groups using the Pearson chi-square test or Fisher's exact test.
Background: This study aimed to adopt computational fluid dynamics to simulate the blood flow dynamics in inferior vena cava stenosis based on time-dependent patient-specific models of Budd-Chiari syndrome as well as a normal model. It could offer valuable references for a retrospective insight into the underlying mechanisms of Budd-Chiari syndrome pathogenesis as well as more accurate evaluation of postoperative efficacy.
Methods: Three-dimensional inferior vena cava models of Budd-Chiari syndrome patient-specific (preoperative and postoperative) and normal morphology model were reconstructed as per magnetic resonance images using Simpleware.
Background: The purpose of this study was to investigate the feasibility of the non-invasive assessment of hemodynamic parameters with computational fluid dynamics in left anterior descending coronary artery based on invasive fractional flow reserve.
Methods: A left coronary artery model based on computed tomography angiography was reconstructed using MIMICS 18.0 for computational fluid dynamics analysis.