ATM-R: An Adaptive Tradeoff Model With Reference Points for Constrained Multiobjective Evolutionary Optimization.

The goal of constrained multiobjective evolutionary optimization is to obtain a set of well-converged and well-distributed feasible solutions. To achieve this goal, a delicate tradeoff must be struck among feasibility, diversity, and convergence. However, balancing these three elements simultaneously through a single tradeoff model is nontrivial, mainly because the significance of each element varies in different evolutionary phases.

iBT-Net: an incremental broad transformer network for cancer drug response prediction.

In modern precision medicine, it is an important research topic to predict cancer drug response. Due to incomplete chemical structures and complex gene features, however, it is an ongoing work to design efficient data-driven methods for predicting drug response. Moreover, since the clinical data cannot be easily obtained all at once, the data-driven methods may require relearning when new data are available, resulting in increased time consumption and cost.

CircRNA circ_POLA2 overexpression suppresses cell apoptosis by downregulating PTEN in glioblastoma.

The oncogenic role of circ_POLA2 has only been explored in lung cancer, whereas the role of which in glioblastoma (GBM) is unclear. Our research explored the involvement of circ_POLA2 in GBM. Circ_POLA2 and phosphatasetensinhomolog (PTEN) mRNA levels in GBM and paired nontumor tissues collected from 58 GBM patients were analyzed by real-time quantitative PCR (RT-qPCR).

Prognosis and Influencing Factors of Early Microsurgery for Severe Hypertensive Brainstem Hemorrhage.

Objective: To investigate the prognosis and influencing factors of early microsurgery for severe hypertensive brainstem hemorrhage.

Methods: The clinical data of 19 patients with severe hypertensive brainstem hemorrhage treated in the Department of Neurosurgery of the Second Affiliated Hospital of Shandong First Medical University between January 2018 and December 2021 were retrospectively analyzed. The clinical efficacy and risk factors affecting the prognosis were analyzed by chi-square test and multivariate logistic regression.

circ_0082375 promotes the progression of glioma by regulating Wnt7B.

Circular RNAs contribute to the progression of glioma. However, the biological role and underlying mechanism of circ_0082375 in glioma remain unclear. Quantitative real-time PCR and Western blot assay were used to evaluate the expression levels of circ_0082375, microRNA-485-5p, and Wnt family member 7B (Wnt7B).

Infarct volume and outcome of cerebral ischaemia, a systematic review and meta-analysis.

Background: Multiple studies have evaluated the accuracy of infarct volume (IV) as a predictor of outcome in patients with ischaemic stroke; however, no study has systematically reviewed the results of these studies.

Aim: This systematic review and meta-analysis aim to sum up the results of the studies evaluating IV as the prognostic criteria for patients with cerebral ischaemia.

Methods: Human studies that reported the infarction volume and any prognostic outcome in patients with ischaemic stroke were collected from PubMed, Scopus, Embase and Cochrane library databases.

Clustering Ensemble Based on Hybrid Multiview Clustering.

As an effective method for clustering applications, the clustering ensemble algorithm integrates different clustering solutions into a final one, thus improving the clustering efficiency. The key to designing the clustering ensemble algorithm is to improve the diversities of base learners and optimize the ensemble strategies. To address these problems, we propose a clustering ensemble framework that consists of three parts.

New use for spent coffee ground as an adsorbent for tetracycline removal in water.

Spent coffee grounds (SCG-1 and SCG-2) were used to study the adsorption of tetracycline (TC) antibiotics and the effects of adsorption time, initial pH, amount of adsorbent and ionic strength were detected. The TC adsorption isotherm on SCG-1 was compared with SCG-2. The results showed that the removal efficiencies of TC (50 mg/L) of SCG-1 and SCG-2 were 83.

Molecular pathological expression in malignant gliomas resected by fluorescein sodium-guiding under the YELLOW 560 nm surgical microscope filter.

Background: This study aimed to analyze the relationship between molecular pathologic expression of GFAP and Ki-67 and fluorescence levels, and to provide molecular pathological basis for the removal of malignant gliomas (MG) by Fluorescein Sodium (FLS) navigation under the YELLOW 560 nm surgical microscope filter.

Methods: A retrospective analysis of clinical data of 18 MG cases confirmed by the postoperative pathology was performed. All cases were resected by FLS guiding under the YELLOW 560 nm filter.

Upgrading liquor-making wastewater into medium chain fatty acid: Insights into co-electron donors, key microflora, and energy harvest.

Ethanol and lactate are considered suitable electron donors (EDs) for chain elongation (CE); however, their respective shortcomings still limit the substrate conversion ratio and medium chain fatty acid (MCFA) production. To address this limitation, different EDs and electron acceptors (EAs) were combined to compare their CE performances, and to investigate whether the combination of ethanol and lactate could further enhance the MCFA production based on the complementary characteristics of ethanol and lactate. The results verified, for the first time, ethanol and lactate as the co-EDs formed a cooperative relationship to largely promote the conversion of substrates into MCFA.

Corrigendum to "Sodium Fluorescein-Guided Resection under the YELLOW 560 nm Surgical Microscope Filter in Malignant Gliomas: Our First 38 Cases Experience".

[This corrects the article DOI: 10.1155/2017/7865747.].

Sodium Fluorescein-Guided Resection under the YELLOW 560 nm Surgical Microscope Filter in Malignant Gliomas: Our First 38 Cases Experience.

Objective: Sodium fluorescein (FL) had been safely used in fluorescence-guided microsurgery for imaging various brain tumors. Under the YELLOW 560 nm surgical microscope filter, low-dose FL as a fluorescent dye helps in visualization. Our study investigated the safety and efficacy of this innovative technique in malignant glioma (MG) patients.