Publications by authors named "Xianbin Ding"

Objectives: Human behaviors and blood pressure (BP) are closely intertwined, affecting health. However, few studies have demonstrated their complex relationships. Using network analysis, we aimed to untangle the intricate and potential causal relationships between BP and human instinctive behaviors, identifying potential action points for hypertension prevention and control.

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Background: This study aimed to identify the main dietary patterns in Hechuan and clarify how they are associated with obesity phenotypes.

Methods: A cross-sectional study was conducted based on a baseline survey of a general population cohort study in southwest China. A semi-quantitative food frequency questionnaire (FFQ) was used to investigate the dietary habits of the participants in the past year.

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Background: Capsaicin is the main component of chili peppers and is believed to have antidiabetic effects. However, the association between spicy food consumption and the incidence of diabetes remains unclear.

Methods: A cohort of 20,490 Han residents aged 30-79 without diabetes at baseline were followed from enrollment to June 2, 2023.

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Background: Homeostatic dysregulation (HD), the measure of aging-related physiological dysregulation, serves as an essential intervenable indicator of aging.

Objective: To explore the associations of three healthy dietary patterns with HD, investigate the most recommended dietary patterns, and identify the significant beneficial and harmful food groups METHODS: This prospective cohort study included 8,288 participants aged 30-79 years from the China Multi-Ethnic Cohort (CMEC), with a female majority (61.6%).

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(1) Background: There is little known about the relationship between Dietary Approaches to Stop Hypertension (DASH) pattern and diabetes in cohort studies, and the dietary patterns in the Chongqing natural population are unknown. (2) Methods: 14,176 Chinese adults, aged 30-79 years old, participated in this prospective study, from September 2018 to October 2023. A dietary assessment was conducted using a food frequency questionnaire, and three main dietary patterns were extracted from the principal component analysis.

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Article Synopsis
  • * Key findings demonstrate that black carbon, organic matter (OM), nitrate, ammonium, chloride, and sulfate all increase CVD risks, with OM and chloride identified as the most significant contributors.
  • * Additionally, the research suggests that the link between OM and CVD is partially mediated by metabolic syndrome, indicating a small contribution (1.3%) of metabolic pathways in this association.
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  • A study investigated the impact of alcohol consumption on hyperuricaemia (HUA) using data from 20,833 participants aged 30-79 in the Chongqing region of China.
  • Participants completed a standardized questionnaire detailing their demographics and alcohol habits, with measurements taken for uric acid, blood glucose, and blood lipids.
  • Results indicated that frequent (3-5 days a week) and harmful alcohol consumption significantly increased the risk of HUA, especially among men, with moderate drinking also posing a risk in certain cases.
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Background: While spicy food is believed to have cardiovascular-protective effects, its impact on hypertension remains uncertain due to conflicting findings from previous studies. This study aimed to explore the association between spicy food and hypertension in Sichuan Basin, China.

Methods: The baseline data of 43,657 residents aged 30-79 in the Sichuan Basin were analyzed including a questionnaire survey (e.

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Background: The incidence of stroke in China is increasing, along with a clear trend in the prevalence of risk factors. Alcohol consumption is also a risk factor for stroke. Many cohort studies have explored the relationship between alcohol consumption and stroke risk.

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Introduction: Stroke has become a major disease that threatens the global population's health and is a major public health problem that needs to be solved in China. Therefore, it is essential to analyze the trend of the mortality of stroke and its epidemic characteristic of stroke death.

Methods: Death cases of stroke were reported to the national death registry system by the medical staff of all medical institutions, and the population data every year were obtained from District or County's Statistic Bureau in Chongqing.

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Background: It is true that Chronic obstructive pulmonary disease (COPD) will increase social burden, especially in developing countries. Urban-rural differences in the lagged effects of PM2.5 and PM10 on COPD mortality remain unclear, in Chongqing, China.

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Objective: The prevalence of hyperuricemia appears to be high worldwide. We aimed to explore the interaction between harmful alcohol use and tea consumption on hyperuricemia.

Methods: This study recruited 22,449 Han residents based on the data from the China Multi-Ethnic Cohort (CMEC) study, Chongqing province, to have a face-to-face electronic questionnaire, physical examination, and clinical laboratory tests.

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  • The study examines how green space impacts mortality rates from Chronic Obstructive Pulmonary Disease (COPD) in Chongqing, China, using data from over 313,000 deaths from 2012 to 2020.
  • Researchers discovered a non-linear relationship between green space, measured by Fractional Vegetation Cover (FVC), and COPD mortality rates with varied effects across different regions.
  • The findings indicate that while 63% of areas show a positive correlation between green space and COPD mortality, 37% display a negative correlation, suggesting that green space may be a risk factor for COPD mortality in certain regions.
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  • This study investigates the link between spicy food intake, the DASH diet score, and the occurrence of stroke among 22,160 Han residents in southwest China over approximately 45 months.
  • Results show that eating spicy food can lower stroke risk by 34% in individuals with low DASH scores, while those with high DASH scores who don't consume spicy food have a 46% lower incidence of stroke.
  • The findings suggest that the protective effects of spicy food and the DASH diet may interact negatively, indicating that their benefits may not work together effectively to reduce stroke risk in those aged 30-79.
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Background: Although there are several cross-sectional and prospective studies on the relationship between sleep duration /insomnia symptoms and depression symptoms, the results of these studies are still not conclusive, and few studies have further analyzed the association between sleep duration and depressive symptoms in adults by gender and age. Thus, this study aimed to investigate the relationship between nocturnal sleep duration and insomnia symptoms with depression symptoms, and further examine whether the association was impacted by age and gender in a large-scale Han Chinese population in southwest China.

Methods: A cross-sectional study was performed that included 44,900 participants from 18 districts in southwest China from September 2018 to January 2019.

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Background: Few animal experiments and volunteer-based intervention studies have showed a controversial effect of spicy foods on abdominal obesity. We aimed to examine the association between spicy food frequency, spicy flavor, and abdominal obesity among Chinese Han population in the Sichuan Basin which area eating spicy foods relatively often.

Methods: A cross-sectional analysis was conducted using the Sichuan Basin baseline data from the China Multi-Ethnic Cohort (CMEC) study, including data from electronic questionnaires, anthropometric measurements and blood sample collection.

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Unlabelled: This paper is an evaluation of seasonal influenza vaccination hesitancy (IVH) and its determinants among community HCWs in Chongqing, a city in southwest China.

Methods: A cross-sectional survey of 1030 community HCWs with direct or indirect patient contact was conducted from July to September 2021 using a self-administered electronic questionnaire. Possible factors for IVH among community HCWs were investigated by multivariable logistic regression to yield adjusted odds ratios (ORs) and 95% confidence intervals (CIs).

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Hyperuricemia is associated with substantial health and economic burden all over the world. Dietary habits are an important influencing factor of hyperuricemia. This study aimed to investigate the relationship between spicy food intake and hyperuricemia based on a large population.

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Background: Existing studies on the association of age at menarche and age at natural menopause with diabetes are conflicting.

Objective: To explore the associations of age at menarche and age at natural menopause with diabetes, and to estimate whether body mass index, abdominal obesity, hypertension, and dyslipidemia would influence the relationships.

Methods: In this cross-sectional study, 5090 postmenopausal women were included from the China Multi-Ethnic Cohort Study (CMEC) baseline in Chongqing province.

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The aim of our study was to examine the relationship between age at menarche (AM) and hypertension and to evaluate whether different dietary patterns have an effect on associations between AM and hypertension in a large-scale Han Chinese population in southwest China. A cross-sectional study was performed that included 44,900 participants from 17 districts in southwest China from September 2018 to January 2019. The study comprised 23,805 individuals in the final analysis.

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Article Synopsis
  • Wide pulse pressure (WPP) is linked to arterial stiffness and cardiovascular issues, and long-term exposure to particulate matter (PM) increases the risk of WPP.
  • The study identifies at-risk groups based on demographic, health, and lifestyle factors, revealing that certain subpopulations (like those with high BMI or inflammation markers) are more vulnerable to WPP from PM exposure.
  • Findings emphasize the importance of targeted prevention strategies to reduce health risks associated with air pollution.
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Objective: To examine the relationship between self-reported snoring and hyperuricaemia in a large-scale population in Chongqing, China.

Setting: Face-to-face electronic questionnaire survey, physical examination and biological sample testing were conducted in 13 districts of Chongqing. Chongqing is a municipality in southwest China.

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  • The study investigates the link between snoring frequency and diabetes in premenopausal and postmenopausal women, considering how menopause impacts this relationship.
  • Data was collected from over 12,000 women using questionnaires, physical exams, and biological samples, utilizing logistic regression to analyze the results.
  • The findings reveal that snoring increases diabetes risk, particularly in women who are frequently snoring, with the highest risk observed in those over ten years postmenopausal.
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  • Long-term exposure to ambient air pollution (AP) is linked to higher prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) in a study of over 90,000 participants in China.
  • The research found that higher levels of four types of air pollutants significantly increased the odds of developing MAFLD, with specific odds ratios indicating the risk associated with each pollutant.
  • Certain factors, such as being male, drinking alcohol, smoking, having a high-fat diet, and being centrally obese, intensified the negative impact of air pollution on MAFLD risk.
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