Placental site trophoblastic tumor in the pelvic wall: a case report and review of the literature.

Extra-uterine placental site trophoblastic tumor (PSTT) is extremely rare. To our knowledge, PSTT that occurs in the pelvic wall has not yet been reported. A 29-year-old woman presented with amenorrhea and irregular vaginal bleeding of 1 month.

Granular cell tumor of the uterine cervix. A case report.

Background: Granular cell tumor (GCT) is a relatively rare and nearly always benign neoplasm that has been described in many sites and organs including the tongue, skin, subcutaneous tissue, breast, and vulva. However, it is rarely seen in the uterine cervix.

Case: We report a case of granular cell tumor of the cervix in a 38-year-old woman.

[Primitive neuroectodermal tumor in female genital tract: a clinicopathologic study].

Objective: To study the clinicopathologic features of primitive neuroectodermal tumor (PNET) in female genital tract.

Methods: Six cases of PNET arising in female genital tract were retrospectively reviewed. The clinicopathologic features, immunohistochemical findings and EWS gene translocation study results were analyzed.

[Malignant transformation of ovarian endometriosis: a clinicopathologic analysis of 49 cases].

Background & Objective: Ovarian endometriosis is a common and benign, but progressive disease. We aimed to investigate the clinicopathologic of ovarian endometriosis with malignant transformation and to evaluate the expression differences of estrogen receptor (ER) and progesterone receptor (PR) between ovarian endometriosis samples with and without malignant transformation.

Methods: Clinicopathologic data of 49 ovarian endometriosis patients with malignant transformation were reviewed.

[Relation between the expression of hypoxia inducible factor-1alpha and angiogenesis in ovarian cancer using tissue microarray].

Objective: To study the relation between the expression of hypoxia inducible factor-1alpha (HIF-1alpha)and angiogenesis in ovarian cancer.

Methods: The expressions of HIF-1alpha mRNA, vascular endothelial growth factor (VEGF), and CD(34) in 295 patients with epithelial ovarian tumors were analyzed by tissue microarray technology, in situ hybridization and immunohistochemistry, and compared with those of 13 normal ovarian tissue samples.

Results: The expressions of HIF-1alpha mRNA were observed in 0, 13.

[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship].

Objective: To detect the expressions of matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) in cervical cancer and their correlation with clinicopathologic features.

Methods: With the use of specific monoclonal antibody to human MMP-2 and MMP-9, the formalin-fixed and paraffin-embedded specimens of 62 invasive carcinomas of cervix uteri, 5 carcinomas in situ, 10 normal cervical epithelia and 10 lymph node metastases were detected by immunohistochemical method.

Results: MMP-2 and MMP-9 protein expressions in tumor and peritumoral stromal cells were enhanced in invasive carcinoma, compared to those in carcinoma in situ and controls (P < 0.