Dihydrophenanthro[]furan derivatives from the tubers of .

Two pairs of new dihydrophenanthro[]furan enantiomers blephebibnols G-H (), one new dihydrophenanthro[]furan derivative blephebibnol I (), along with four known analogues (), were isolated from the tubers of . Their structures including the absolute configurations were determined by the combination of spectroscopic data analysis, ECD and NMR calculations. Compounds , , and showed inhibition of NO production in LPS-stimulated BV-2 cells, with IC values ranging from 4.

Platelet-Rich Fibrin in Fat Grafts for Facial Lipofilling: A Randomized, Controlled Split-Face Clinical Trial.

Objective: Previous studies have reported that platelet-rich fibrin (PRF) may enhance the efficacy of fat grafts in facial lipofilling. However, these studies either lacked objective data or were not randomized, controlled trials. Thus, we aimed to objectively evaluate the efficacy of PRF in facial lipofilling.

[Repair of cervical scar contracture with flaps containing cervical cutaneous branch of the transverse cervical artery].

Objective: To observe the therapeutic effect of repairing cervical scar contracture using flaps carrying cervical cutaneous branch of the transverse cervical artery.

Methods: Sixty-six patients with scar contracture after burn in anterior region of neck hospitalized from 1988 to 2011. The scars were excised and repaired with flaps containing the cervical cutaneous branch of transverse cervical artery.

[Repair of inframammary scars with expanded skin flaps].

Objective: To investigate suitable treatment method for contracture of inframammary scars.

Methods: Nine female patients with contracture of inframammary sear hospitalized in our hospital from July 2000 to July 2007 were subjected to skin expansion around the breast. The sites of incisions were mainly located on the inframammary scars.

[Expanded deltopectoral flaps for treatment of cervical cicatricial contracture].

Objective: To investigate the application of expanded deltopectoral flaps for treatment of cervical cicatricial contracture.

Methods: The cervical cicatricial contracture was corrected in 18 cases with unilateral expanded deltopectoral flaps and 2 cases with bilateral expanded deltopectoral flaps. The size of scar ranged from 8 cm x 5 cm to 12 cm x 13 cm.

Effect of camptothecin on collagen synthesis in fibroblasts from patients with keloid.

Keloids are distinguished by substantial deposition of collagen in the dermis, resulting in an imbalanced production and aggregation of extra cellular matrix. This study was undertaken to evaluate the effects of the topoisomerase I inhibitor camptothecin (CPT) on collagen synthesis in the activated dermal fibroblasts from healthy donors and patients with keloid. The fibroblasts were cultured in the presence or absence of CPT.

[Expanded skin flaps for the treatment of large scalp and face scar].

Objective: To explore the method to repair large scalp and face scars.

Methods: 1-3 expanders under the scalp were needed for repair the scalp scar. The expanded deltopectoral flaps were transferred to repair the face scar.

[Repair of facial and cervical scars with expanded deltopectoral flaps].

Objective: To explore the methods for repair of facial and cervical scars after burn.

Methods: One hundred and two patients with facial and cervical scars as a result of burn injury were repaired by unilateral or bilateral deltopectoral flaps after expansion with pedicles. First, facial scars were excised and contractures were released to restore eye, mouth and nose to normal anatomical position.

[The design of the expanded flap for the repair of the temporal and cheek area].

Objective: To explore the design of an expanded flap at the temporal and cheek area.

Methods: The expanded flap was used for the repair of 619 temporal and cheek defects secondary to scar, nevus or hemangioma excision. In the frontal area, the rotational flap was usually used.

[Management of severe postburn scar contracture in the lower extremities].

Objective: To summarize the clinical experience in the management of severe postburn scar contracture in the lower extremities.

Methods: The scars in popliteal fossa and ankle joint were excised. Traction and skin grafting were employed in the management of contracture deformity in these areas.