Identification of candidate biomarkers associated with gastric cancer prognosis based on an integrated bioinformatics analysis.

Background: This study sought to identify candidate biomarkers associated with gastric cancer (GC) prognosis based on an integrated bioinformatics analysis.

Methods: First, the GSE54129 and GSE79973 data sets were downloaded from the Gene Expression Omnibus (GEO) database. The differentially expressed genes (DEGs) identified between the 2 data sets were screened using the limma software package in R, and the intersection DEGs were obtained by a Venn analysis.

[Development and model of health education and health promotion for schistosomiasis control in mountainous and hilly endemic areas].

Transmission control and interruption of schistosomiasis has been gradually achieved in the mountainous and hilly endemic areas with the implementation of the schistosomiasis control programmes, which are moving towards the progress of schistosomiasis elimination. As an important measure of schistosomiasis control, health education is experiencing new challenges and problems in the new situation, and conventional health education of schistosomiasis control has already failed to meet the needs of socioeconomic and cultural development and the increasing changes of human production and life styles in the endemic areas. Therefore, a precision health education model for schistosomiasis control is of great need to be established to highly effectively promote the implementation of schistosomiasis control measures.

[Strategy and effect of schistosomiasis emergency control after earthquake in Lushan County].

Objective: To evaluate the effects of measures on the schistosomiasis control after the earth quake in Lushan County, so as to provide the experiences for post-disaster schistosomiasis control.

Methods: The measures taken in schistosomiasis control after the earth quake were reviewed in Lushan County in 2013, and the epidemic situation of schistosomiasis was investigated and the results were analyzed.

Results: The schistosomiasis control in floating population and the control of Oncomelania hupensis snails were enhanced, and no schistosome infections were found in both human and livestock.

[Assessment of schistosomiasis transmission interruption in Beichuan County, Sichuan Province].

Objective: To assess whether Beichuan County reaches the national standard of schistosomiasis transmission interruption.

Methods: Three villages in Beichuan County were sampled as assessment spots, and the schistosomiasis infections of residents and domestic animals, the status of Oncomelania snails and the past records were assessed according to the Criteria for Control and Elimination of Schistosomiasis in China.

Results: No local schistosome infections were found in residents and cattle for successive 5 years and no snails were found for 2 successive years in the 3 villages.

[Toxicity of 50% ethanol salt powder of niclosamide on growth of silkworms].

Objective: To observe the toxity of niclosamide on the growth of silkworms.

Methods: Mulberry leaves were soaked in the different concentrations of solution of 50% ethanol salt powder of niclosamide for 10 s or 3 min, and then the leaves were fed to silkworms. The death rates of silkworms and the weight of cocoons were observed.

Genomic organization and promoter characterization of FcCTL, a C-type lectin-like protein in Fenneropenaeus chinensis.

Diseases caused by viruses are the greatest challenge to worldwide shrimp aquaculture. C-type lectins may play an important role in shrimp immunity. The gene encoding FcCTL, a C-type lectin-like protein, was isolated from Fenneropenaeus chinensis and characterized.

[Surveillance of schistosomiasis in Sichuan Province, 2005-2010].

Objective: To understand the epidemic trend of schistosomiasis in Sichuan Province so as to provide the evidence for formulating schistosomiasis control strategy.

Methods: According to the National Schistosomiasis Surveillance Protocol, the national surveillance sites in Sichuan Province were selected. The schistosomiasis surveillance was carried out continuously from 2005 to 2010.

[Compliance of film-coated praziquantel tablets in schistosomiasis transmission-controlled areas].

Objective: To observe the compliance of film-coated praziquantel tablets in the schistosomiasis transmission controlled areas, so as to provide the evidence for the establishment of chemotherapy intervention measures in these areas.

Methods: In the areas of schistosomiasis transmission controlled in Sichuan Province, 234 people were selected as film-coated praziquantel group (FCPG), and 203 people were selected as praziquantel group (PG). A questionnaire survey was implemented and the compliance of chemotherapy of the 2 groups was compared.

A TaqMan real-time PCR assay for quantifying type III hepatopancreatic parvovirus infections in wild broodstocks and hatchery-reared postlarvae of Fenneropenaeus chinensis in Korea.

A highly sensitive and specific TaqMan real-time PCR was used to quantify hepatopancreatic parvovirus (HPV) type III infections in wild broodstocks and hatchery-reared postlarvae (PL) of Fenneropenaeus chinensis. Totals of 159 and 162 wild brooders from three locations were captured, and 140 and 180 PL were obtained from seven and six commercial hatcheries in 2007 and 2008, respectively. Among the three wild broodstock groups from 2007, only 1 group showed HPV infection and 3.

Multivariate prognostic study on node-positive gastric cancer: is tumor size a prognostic indicator?

Background/aims: We analyzed the clinicopathological factors of patients with node-positive gastric cancer, evaluated the prognostic factors associated with long-term survival and clarified the effect of tumor size on long-term survival.

Methodology: The study included 591 patients who underwent curative resection for node-positive gastric cancer. Clinicopathological prognostic variables were evaluated as predictors of long-term survival by univariate and multivariate analyses.

[Modeling transmission dynamics and control of schistosomiasis in the mountainous region, Sichuan].

Objective: To use a mathematical model and computer simulation to study transmission dynamics and control of schistosomiasis in mountainous regions of Sichuan.

Methods: Based on studies of schistosomiasis japonica transmission in 20 villages in mountainous regions of Sichuan, a mathematical model was developed to characterize the impact of local environmental factors on transmission intensity. The model integrated site-specific factors and was calibrated to field epidemiological data from 3 subset villages.