Publications by authors named "Xian-gui He"
Purpose: Previous animal studies have found a relationship between spatial frequency and myopia. New research in humans suggest that reduced high spatial content of the visual environment may be a contributing factor for myopia development. This study aims to review the literature and elucidate the potential biological mechanisms linking spatial frequency and myopia.
View Article and Find Full Text PDFBackground: This study examined the moderating role of outdoor time on the relationship between overweight and myopia.
Methods: The data for this study was obtained from a prospective study in Shanghai, where non-myopic children wore wristwear and were followed up for 1 year. Eye examinations were performed at each visit.
Article Synopsis
- Myopic retinopathy is a significant cause of irreversible vision loss, particularly in children and adolescents, and this study aimed to analyze serum metabolic profiles related to the condition while developing a diagnostic model.
- Researchers utilized clinical and serum metabolic data from 576 participants and found that 34.2% had retinopathy, with notable differences in 27 metabolites between groups, indicating potential issues with energy metabolism.
- The study successfully created machine learning models, specifically logistic regression and XGBoost, that accurately predicted myopic retinopathy risk, supporting the idea that combining metabolic and clinical data can lead to more effective interventions for managing myopia in young people.
Article Synopsis
- The study aimed to investigate how photopic pupil size (PPD) changes in myopic children undergoing overnight orthokeratology (ortho-k) and how this affects their eye growth over a year.
- A total of 202 Chinese myopic children participated, with those in the ortho-k group showing slower axial elongation compared to the spectacle group (0.25 mm vs. 0.44 mm).
- Results suggested that smaller PPD (specifically ≤4.81 mm) correlated with less axial elongation, indicating that children with smaller pupil sizes may benefit more from ortho-k treatment in terms of eye growth.
Aim: To explore the distribution pattern of macular choroidal thickness (ChT) and its association with age as well as refractive status in Chinese preschoolers.
Methods: School-based, cross-sectional study. A total of 550 healthy preschool children aged 3 to 6 years old from 6 kindergartens were enrolled.
The measurement of time spent outdoors in child myopia research: a systematic review.
Int J Ophthalmol
June 2018
The purpose of this article is to summarize the methods most commonly used to measure time spent outdoors and provide a comprehensive review of time and activity recording methods with the aim of encouraging the development of new methods. PubMed, Embase and the Cochrane Library were searched from Jan. 1, 1990 to Aug.
View Article and Find Full Text PDFBackground: To retrospectively compare axial elongation in children with different degrees of myopia wearing spectacles and undergoing ortho-k treatment.
Methods: The medical records of 128 patients who were fitted with spectacles or orthokeratology (ortho-k) lenses in our clinic between 2008 and 2009 were reviewed. Ortho-k group comprised 65 subjects and 63 subjects wearing spectacles were included in the control group.
[Analysis of cataract surgical rate and its influencing factors in Shanghai, China].
Zhonghua Yi Xue Za Zhi
December 2013
Objective: To explore the cataract surgical rate (CSR) of Shanghai from 2006 to 2012 and examine its influencing factors.
Methods: As of 2003, a cataract surgery registration form had been filled by physicians after every cataract surgery in Shanghai. The local eye disease prevention team then entered the relevant information into the Shanghai Cataract Operations Database.
Background: The control of blindness in children is a high priority within the VISION 2020 initiative. To determine the causes of severe visual impairment and blindness in children from Shanghai Blind Children School (SBCS) can provide useful information on childhood blindness in Shanghai.
Methods: A cross-sectional investigation of students in SBCS was conducted in May 2010.
Objective: To investigate the prevalence of blindness and low vision and the leading causes of blindness in residents aged≥60 years in Dachang Blocks of Baoshan District, Shanghai, China.
Methods: A cross-sectional study was carried out by Shanghai Eye Disease Prevention & Treatment Center and the Center for Disease Control and Prevention in Baoshan District of Shanghai from October to December in 2009. Randomly cluster sampling was used to identify the adults aged≥60 years who had lived in Dachang Blocks of Baoshan District, Shanghai for more than 10 years.