[Response of vegetation productivity to drought in the Qinling-Daba Mountains, China from 2001 to 2020].

To quantitatively evaluate the effects of drought on vegetation productivity in the Qinling-Daba Mountains, we analyzed the temporal and spatial characteristics of gross primary productivity (GPP) and drought, identified the fluctuation of negative GPP extremes under different vegetation types, and quantified the drought vulnerability and drought risk of GPP from 2001 to 2020 with MODIS GPP products and standardized precipitation evapotranspiration index (SPEI). The results showed that the annual GPP from 2001 to 2020 had an increasing trend in 98.0% of areas in the Qinling-Daba Mountains.

[Research progress on the cascade effect of ecosystem service.].

The ecosystem services cascade (ESC), which connects the components of ecosystem services with social value and builds a bridge between natural science and social science, can help decision-makers better integrate the concept of ecosystem services into decision-making. We reviewed the concept and the research progress of ESC. From the perspective of theory, the theoretical research of ESC mainly focused on how to accurately define each component and the causal relationship among different components, improve the practicability and applicability of ESC model, and how to effectively connect stakeholders and ecosystem service structure.

MiR-31 is a potential biomarker for diagnosis of head and neck squamous cell carcinoma.

MicroRNAs (miRNAs) play important roles in the development of head and neck squamous cell carcinoma (HNSCC). However, their potential clinical value as biomarkers remains poorly known. The aim of this study was to assess the association between tissue/serum miR-31 expression levels and prognosis of HNSCC.

Cancer risk assessment in modern radiotherapy workflow with medical big data.

Modern radiotherapy (RT) is being enriched by big digital data and intensive technology. Multimodality image registration, intelligence-guided planning, real-time tracking, image-guided RT (IGRT), and automatic follow-up surveys are the products of the digital era. Enormous digital data are created in the process of treatment, including benefits and risks.

A parameterized model for mean urinary inflow rate and its preliminary application in radiotherapy for cervical cancer.

Forty-nine patients with stage II cervical cancer were included to investigate the changes in bladder volume in response to different approaches to maintaining consistent bladder filling. The impacts of age (P ), water consumption (P ), and body mass index (BMI, P ) on the mean urinary inflow rate (v ) were analysed. The bladder volume (BV) increased linearly over time.

[Effect of different doses of radiation on human salivary gland adenoid cystic carcinoma cells].

Purpose: To explore the effect of different doses of radiation on human salivary gland adenoid cystic carcinoma cells (SACC-83, SACC-LM).

Methods: Different doses of radiation (0, 2, 4, 6, 8, 10 Gy) were applied to SACC-83, SACC-LM cells and the cells were continued to culture for 48 h. CCK-8 test, flow cytometry(FCM) and cell scratch experiment were used to observe cell proliferation, apoptosis and cell migration.

Effect of High-Dose Statin Pretreatment on the Incidence of Periprocedural Myocardial Infarction in Patients Undergoing Percutaneous Coronary Intervention: Grading the Evidence Through a Cumulative Meta-analysis.

Background: Previous studies have showed that high-dose statin pretreatment could reduce the incidence of periprocedural myocardial infarction (PMI) in patients undergoing percutaneous coronary intervention (PCI). However, previous analyses have not performed reliable grading of evidence.

Hypothesis: In previous analyses, it supposed that the high-dose statin pretreatment was effective in reduction of the rate of PMI.

Correlation study of Bcl-2, B7-H1, EGFR, VEGF and colorectal cancer.

Objective: To analyze the expressions of Bcl-2, B7-H1, EGFR and VEGF in colorectal cancer for the further investigation of their correlations with the clinical pathological features of colorectal cancer.

Method: Fresh colorectal cancer tissues and the expressions of Bcl-2, B7-H1, VEGF and EGFR in paraneoplastic normal mucosal tissues of 57 cases were tested by immunohistochemisty method, and the results were analyzed by SPSS10.0.

HMGA2 Expression in Renal Carcinoma and its Clinical Significance.

Background: The objective of this study is to detect HMGA2 expression in renal carcinoma to explore its relationship with clinicopathology and its significance in prognosis.

Methods: Expressions of HMGA2 mRNA and protein were detected in 50 renal carcinoma specimens, 50 corresponding adjacent normal kidney tissue samples and 40 renal benign tumour specimens via reverse transcription polymerase chain reaction and immunohistochemical assay. Expression analysis was performed along with clinical data analysis.

Rs7193343 polymorphism in zinc finger homeobox 3 (ZFHX3) gene and atrial fibrillation: an updated meta-analysis of 10 case-control comparisons.

Background: The previous genome-wide studies have shown that rs7193343 single-nucleotide polymorphism (SNP) in zinc finger homeobox 3 (ZFHX3) gene correlate with risk of atrial fibrillation (AF). However, the distribution of this SNP differs significantly among various populations. The present study was to investigate whether combined evidence shows the association between ZFHX3 rs7193343 SNP and the risk of AF in various populations.

[Spatiotemporal variation patterns of potential evapotranspiration in five provinces of Northwest China in 1960-2011].

By using Penman-Monteith model and Hurst index model, this paper analyzed the spatiotemporal variation patterns of potential evapotranspiration (ET0) in the five provinces of Northwest China in 1960-2011. In the meantime, the dominant factors driving the variations of the ET0 were quantitatively analyzed by using sensitivity analysis method. In 1960-2011, the ET0 in the five provinces presented an overall decreasing trend, with a drop rate of -0.

Dosimetric evaluation of volumetric-modulated arc therapy (RapidArc) for primary leiomyosarcoma in the spine.

This study aims to investigate the suitability of volumetric-modulated arc therapy (VMAT) with RapidArc for primary leiomyosarcoma (LMS) in the spine, and present a new method to improve the target coverage and organs at risk (OAR) sparing. Five patients with LMS were retrospectively reviewed. The intensity-modulated radiotherapy (IMRT) with five coplanar beams (5b-IMRT) or seven coplanar beams (7b-IMRT), and VMAT using four quasi-quarter coplanar arcs (4q-VMAT) or two full coplanar arcs (2f-VMAT) were generated.

Cardiovascular and cerebrovascular outcomes in elderly hypertensive patients treated with either ARB or ACEI.

Background: Although angiotensin converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) are equally important in the treatment of hypertension, there is less evidence whether they have equal cardiovascular and cerebrovascular protective effects, especially in elder hypertensive patients. This study aims to clarify this unresolved issue.

Methods: This cross-sectional study included clinical data on 933 aged male patients with hypertension who received either an ARB or ACEI for more than two months between January 2007 and May 2011.

The molecular mechanism of the anticancer effect of atorvastatin: DNA microarray and bioinformatic analyses.

The aim of this study was to identify the molecular mechanisms and biological pathways associated with the anticancer effects of atorvastatin. For this purpose, we conducted cell-based microarray and bioinformatic analyses to determine the effect of atorvastatin exposure on endothelial cell response. The results of bioinformatic analysis performed using the Connectivity Map (cMap) to examine the atorvastatin-induced changes in gene expression in the human umbilical vein endothelial cell line, EA.

Protective effects of atorvastatin against oxidized LDL-induced downregulation of KLF expression in EA.hy926 cells.

Krüppel-like transcription factors (KLFs) play a key role in both vascular development and pathophysiological processes, but little is known about the relationship between KLFs and oxidized low-density lipoprotein (ox-LDL). We investigated the effects of ox-LDL on KLF expression. Furthermore, since atorvastatin is commonly used to treat high cholesterol, we also examined the role of this drug in the regulation of KLF expression.

Angiogenesis related gene expression profiles of EA.hy926 cells induced by irbesartan: a possible novel therapeutic approach.

Background: Angiogenesis occurs commonly in various physiological and pathological processes. Improving blood supply through promoting angiogenesis is a novel approach for treating ischemic diseases. Angiotensin II type 1 receptor blockers (ARBs) dominate the management of hypertension, but evidence of their role in angiogenesis is contradictory.

[Impact of clopidogrel on gene profile of human umbilical vein endothelial cell line and bioinformatics analysis].

This study was purposed to investigate the effect of clopidogrel on gene expression profile of cultured human umbilical vein endothelial cell (HUVEC) line (EA.hy926), and explore its potential molecule mechanism. A Affymetrix U133 plus 2.

[Effect of irbesartan on the proliferation, apoptosis and VEGF mRNA expression of human umbilical vein cell line ea. hy926 in vitro].

Objective: To evaluate the effect of irbesartan on the proliferation, apoptosis, and VEGF mRNA expression of human umbilical vein cell line EA.hy926 in vitro.

Methods: The human umbilical vein cell line EA.

[Irbesartan regulates inflammatory gene expressions related to atherosclerosis in EA.hy926 cells].

Objective: To characterize if irbesartan regulates vascular inflammatory gene expression profiles related to atherosclerosis in EA.hy926 cells.

Methods: Human umbilical vein endothelial cell line EA.

Oxidative cleavage of hydrobenzoin by ACC/silica gel under ultrasound irradiation.

A mild and efficient method has been developed using ultrasound irradiation for oxidative cleavage of hydrobenzoin with ACC/silica gel in dichloromethane. A high yield of 72-99% has been obtained for the oxidation of a series of hydrobenzoins into aromatic aldehydes at room temperature.