Publications by authors named "Xian-da Chen"
Article Synopsis
- Penile cancer (PC) is a severe form of cancer without reliable prognostic indicators, and this study explores how changes in squamous cell carcinoma antigen (SCC-A) levels relate to patient outcomes following TIP chemotherapy.
- The research analyzed 80 patients with advanced PC, identifying two patterns of SCC-A levels: a low-stable group and a high-decline group, with the latter showing significantly poorer survival and tumor response outcomes.
- The findings suggest that monitoring SCC-A levels could be useful in assessing treatment effectiveness and patient prognosis after chemotherapy.
β-Adrenergic receptor (β-AR) overactivation is a major pathological factor associated with cardiac diseases and mediates cardiac inflammatory injury. Glibenclamide has shown anti-inflammatory effects in previous research. However, it is unclear whether and how glibenclamide can alleviate cardiac inflammatory injury induced by β-AR overactivation.
View Article and Find Full Text PDFObjective: To explore the inhibitory effects of human umbilical cord-derived mesenchymal stem cells (hUCMSC) on the proliferation of peripheral blood mononuclear cells (PBMC) from spondyloarthritis (SpA) patients.
Methods: A total of 12 SpA patients at Chinese PLA General Hospital were recruited from May 2012 to October 2012. Information on demographic characteristics, disease and functional activity was collected.
In this study, the inhibitory effect of human umbilical cord-derived mesenchymal stem cells (hUCMSC) on interleukin-17 (IL-17) production in peripheral blood T cells from patients with spondyloarthritis (SpA) were investigated, in order to explore the therapeutic potential of hUCMSC in the SpA. Peripheral blood mononuclear cells (PBMNC) were isolated from patients with SpA (n = 12) and healthy subjects (n = 6). PBMNC were cultured in vitro with hUCMSC or alone.
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