Publications by authors named "Xian-chao Kong"
Article Synopsis
- CircRNAs, specifically circRNA_101996, play important roles in cervical cancer development and act by regulating miR-8075/TPX2.
- The study found that circRNA_101996 is over-expressed in cervical cancer, promoting cell proliferation, migration, and the cell cycle, while its knockdown shows the opposite effects.
- CircRNA_101996 influences the expression of miR-1236-3p and TRIM37, suggesting that targeting this axis could lead to new diagnostic and therapeutic strategies for cervical cancer.
Intramural pregnancy is a rare type of ectopic pregnancy, where the gestational sac is implanted inside the myometrium instead of the endometrial and fallopian tubes. Preoperative diagnosis remains very difficult. Ultrasonic findings vary according to the anatomical location or duration of pregnancy.
View Article and Find Full Text PDFObjective: The function of Ras-related C3 botulinum toxin substrate1 (Rac1) in the progression of cervical cancer is unclear. This study used RNA interference technology to explore the involvement of Rac1 in the regulation of cervical cancer cells.
Methods: A short hairpin (sh) RNA plasmid targeting Rac1 was constructed and transfected into HeLa cells.
Objective: To evaluate the clinical value of transvaginal elastography (TVES) in diagnosing cervical malignancies by detecting changes of tissue stiffness.
Methods: One hundred and ten consecutive patients with cervical lesions were enrolled. Pathological results were used as the gold standards.
Background: Nucleophosmin plays a critical role in embryonic development. This study aimed to examine the expression pattern of nucleophosmin in glandular epithelium of human endometrium during the menstrual cycle.
Methods: Endometrial tissues used for this study were obtained from 46 non-pregnant patients who underwent hysterectomy which had been performed to treat benign diseases.