Publications by authors named "Xian-Zhe Luo"
Article Synopsis
- The study investigates the connection between serum S100A12 levels and postoperative delirium (POD) and cognitive dysfunction (POCD) in elderly patients after hip fracture surgery.
- Elevated serum S100A12 levels were found only after surgery, correlating strongly with C-reactive protein levels and indicating inflammation.
- High postoperative S100A12 levels and older age independently predicted the risk of developing POD and POCD, suggesting S100A12 as a potential biomarker for these complications.
Background: Cold-inducible RNA-binding protein (CIRP) is a pro-inflammatory cytokine. We determined whether serum or synovial fluid concentrations are associated with severity in osteoarthritis (OA).
Methods: CIRP concentrations in serum and synovial fluid from 156 knee OA patients and serum from 156 controls were determined.
Neuropathic pain is caused by lesion or inflammation of the nervous system and characterized by the symptoms of allodynia, hyperalgesia and spontaneous pain. SIRT1 (Sir2) is a NAD-dependent deacetylase and is reported to regulate a wide variety of cellular processes including inflammation, aging and lifespan extension. Nevertheless, the role of SIRT1 in neuropathic pain is not fully understood.
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