Clinical characteristics and long-term outcomes for parapharyngeal metastases of well-differentiated thyroid cancer during I therapy and follow-up.

Objective: Parapharyngeal metastases (PPM) are rarely observed in patients with well-differentiated thyroid cancer (WDTC). Radioiodine ( I) therapy has been the main treatment for metastatic and recurrent DTC after thyroidectomy. This study was performed to evaluate the clinicopathological features and long-term outcomes associated with survival of patients with PPM at the end of follow-up.

Transoral endoscopic selective lateral neck dissection for papillary thyroid carcinoma: a pilot study.

Background: Transoral endoscopic thyroid surgery via the vestibular approach (TOETVA) has been gradually accepted worldwide due to its scar-free effect on the neck. Even central cervical lymphadenectomy has been performed in some cases of papillary thyroid carcinoma (PTC). However, there are few reports involving lateral neck dissection with TOETVA.

PPM1D exerts its oncogenic properties in human pancreatic cancer through multiple mechanisms.

Protein phosphatase, Mg(2+)/Mn(2+) dependent, 1D (PPM1D) is emerging as an oncogene by virtue of its negative control on several tumor suppressor pathways. However, the clinical significance of PPM1D in pancreatic cancer (PC) has not been defined. In this study, we determined PPM1D expression in human PC tissues and cell lines and their irrespective noncancerous controls.

New endoscopic thyroidectomy with the transareola single-site approach: a comparison with the bilateral areolar approach.

Purpose: We developed the transareola single-site approach (TASSA) for less invasive endoscopic thyroidectomy to avoid scars on exposed areas. Here, we report our experience with the TASSA technique in treatment of benign thyroid tumors and evaluate its feasibility through comparison with the bilateral areolar approach (BAA).

Methods: From September 2009 to December 2011, 129 patients with benign thyroid tumors were enrolled in the study.

Relationships of FOXE1 and ATM genetic polymorphisms with papillary thyroid carcinoma risk: a meta-analysis.

We conducted the meta-analysis of all relevant case-control studies aiming to evaluate the relationships of common polymorphisms in forkhead box E1 (FOXE1) and ataxia telangiectasia mutated (ATM) genes to the risk of papillary thyroid carcinoma (PTC). A range of electronic databases were searched without language restrictions: Web of Science (1945 ~ 2013), the Cochrane Library Database (Issue 12, 2013), PubMed (1966 ~ 2013), EMBASE (1980 ~ 2013), CINAHL (1982 ~ 2013), and the Chinese Biomedical Database (CBM) (1982 ~ 2013). This meta-analysis was conducted using the STATA 12.

Single-port endoscopic thyroidectomy via a submental approach: report of an initial experience.

Background: Based on our experience of trans-areola single-site endoscopic thyroidectomy and a preclinical study in the porcine model, we attempted to develop a new approach called trans-submental single-port endoscopic thyroidectomy (TSSPET).

Methods: Two female patients (43 and 27 years old, respectively) were selected for TSSPET. Both were preoperatively diagnosed with benign thyroid nodule by ultrasonography and fine-needle aspiration cytology (FNAC).