Publications by authors named "Xian-Yi Bao"
Cancer Biomark
January 2022
Article Synopsis
- TRIB3, a pseudokinase, is found to be upregulated in retinoblastoma (RB) and promotes cell proliferation and invasion, revealing its potential role as an oncogene.
- The study utilized various assays to confirm that overexpression of TRIB3 increases the phosphorylation of the AKT and mTOR pathways, while knockdown reduces these effects.
- The findings suggest that targeting TRIB3 could be valuable for diagnosing and treating retinoblastoma.
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