Publications by authors named "Xian-Shuo Zhang"
Macromol Biosci
July 2018
Article Synopsis
- Cyclic brush polymers have been found to be more effective than bottlebrush versions for drug and gene delivery due to their unique structure, but reduction-sensitive variants have not been previously explored.
- This study successfully designed and synthesized a reduction-sensitive amphiphilic cyclic brush copolymer that features a block structure with both hydrophobic and hydrophilic components.
- The resulting micelles display good stability in saline conditions and release drugs more effectively in reducing environments inside cells, highlighting their potential for improved anticancer therapy.
