Identification and validation of a five-gene prognostic signature based on bioinformatics analyses in breast cancer.

Background: This study aimed to identify prognostic signatures to predict the prognosis of breast cancer (BRCA) patients based on a series of comprehensive analyses of gene expression data.

Methods: The RNA-sequencing expression data and corresponding BRCA patient clinical data were collected from the Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) datasets. Firstly, the differently expressed genes (DEGs) related to prognosis between tumor tissues and normal tissues were ascertained by performing R package "limma".

Prognostic Value of Hepatitis B Virus Infection in Very Young Patients With Curatively Resected Breast Cancer: Analyses From an Endemic Area in China.

Hepatitis B virus (HBV) infection has been associated with the risk and prognosis of many malignancies. Nevertheless, the association between HBV and the prognosis of breast cancer is unclear. The objectives of this study were to investigate the prognostic role of hepatitis B surface antigen (HBsAg) and to integrate HBsAg to establish nomograms for better prognostic prediction of very young patients with breast cancer.

Choroidal thickness in school children: The Gobi Desert Children Eye Study.

Purpose: To investigate choroidal thickness (CT) and its associations in children in a school-based study.

Methods: The cross-sectional school-based Gobi Desert Children Eye Study included 1565 out of 1911 (81.9%) eligible children from all schools in the oasis region of Ejina in the Gobi Desert.

Prevalence of myopia in schoolchildren in Ejina: the Gobi Desert Children Eye Study.

Purpose: To determine the prevalence and associations of myopia in schoolchildren in provincial Western China.

Methods: In the school-based observational cross-sectional Gobi Desert Children Eye Study, cylcoplegic refractometry as part of a comprehensive ophthalmic examination was performed in all schools in the oasis region of Ejina. Out of 1911 eligible children, 1565 (81.

Intraocular pressure and associations in children. The Gobi Desert Children Eye Study.

Purpose: To assess the intraocular pressure (IOP) and its association in children in a population living in an oasis in the Gobi Desert.

Methods: The cross-sectional school-based study included all schools in the Ejina region. The children underwent an ophthalmic examination, non-contact tonometry and measurement of blood pressure and body height and weight.