The existence of a putative post-transcriptional regulatory element in 3'-UTR of Drosophila antibacterial peptide diptericin's mRNA.

Antibacterial peptides' genes are rapidly and transiently expressed on immune stimulation, which is the characteristic of immediate early genes. It implies post-transcriptional regulation is an important pathway in antibacterial peptides' gene expression. In a search of putative post-transcriptional regulatory elements, we found a segment of an AU-rich sequence in 3'-untranslated region (UTR) of drosophila diptericin mRNA.

Purification of Recombinant GM-CSF/IL-3 Fusion Protein.

As a new artificial haemopoietic growth factor, GM-CSF/IL-3 fusion protein appears very promi-sing to be developed as a drug in the treatment of many diseases including cancer. The purification process of the recombinant GM-CSF/IL-3 fusion protein was studied. Similar to majority of the eukaryotic proteins, GM-CSF/IL-3 was expressed as inclusion bodies in E.