Attempts have been made to observe the tissue repair of neo-esophagus after esophageal muscularis resection and to investigate possibility of the regeneration repair of esophageal muscularis resection in neo-esophagus. Sixteen pigs were divided into two groups: group A and group B. Pigs in group A were performed with the partial resection of mere esophageal muscularis propria reserved mucosa muscle layer in a segment of thoracic esophagus.
View Article and Find Full Text PDFAttempts have been made to investigate the effect of slip time of nitinol artificial esophagus for forming neo-esophageal stenosis after replacement of a thoracic esophagus with nitinol artificial esophagus in 20 experimental pigs. The pigs whose slip time was less than 90 days postoperatively had severe dysphagia (Bown's III) immediately after they were fed, and the dysphagia aggravated gradually later on (Bown's III-IV). The pigs whose slip time was more than 90 days postoperatively had mild/moderate dysphagia (Bown's I-II) immediately after they were fed, and the dysphagia relieved gradually later on (Bown's II-I-0).
View Article and Find Full Text PDFPurpose: This study attempted to observe the effect of feeding regulation measures (FRM) for the construction of an esophageal channel function in a neoesophagus using an artificial nitinol esophagus.
Methods: Experiments were divided among groups: group 1, receiving FRM; and group 2, the non-feeding regulation measures (NFRM) group.
Results: Ten pigs survived for 6 months without any complications such as anastomotic leakage.
Attempts were made to observe long-term form and function of neoesophagus with three pigs that survived for more than 42 months after Nitinol composite artificial esophagus replacement. The neoesophagus was shorter in length than resected esophagus (shorten rate 13.9 +/- 3.
View Article and Find Full Text PDFZhonghua Yi Xue Za Zhi
September 2009
Objective: To observe the impact of artificial esophagus slipped time upon the function formation of neoesophageal channel, explore the scope of secure control time and assess the treatment methods of neoesophageal stenosis.
Methods: A total of 18 pigs in which artificial esophagus slipping at Month 1, 2, 3, 6 post-operation were observed with regards to complications, neoesophageal structures and functions and survival status of experimental animals.
Results: Three pigs had a slip of artificial esophagus within a month post-operation and severe eating difficulties (Bown's Grade IV) because the neoesophagus had a severe narrowing (< 0.
In a previous study, we replaced a thoracic esophagus with nitinol composite artificial esophagus. Two major problems of anastomotic leakage and early sloughing of the grafted prostheses were noted. We have developed a new type of nitinol composite artificial esophagus with polyester connecting ring, and in this study, we test the effectiveness of replacing a thoracic esophagus with this new type of tube.
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