Publications by authors named "Xian-Lei Lao"
Article Synopsis
- A study utilized an OSMAC (One Strain Many Compounds) strategy to investigate the secondary metabolites and anti-inflammatory effects of the endophytic fungus Penicillium herquei JX4 found in the plant Ceriops tagal.
- The researchers isolated, purified, and identified compounds from the fungus using various chromatography techniques, leading to the discovery of two new pinophol derivatives, pinophol H(1) and pinophol I(2).
- Among these derivatives, pinophol H(1) exhibited strong inhibitory activity against nitric oxide production in mouse macrophage cells, demonstrating its potential as an anti-inflammatory agent with an IC_(50) value of 8.12 μmol