Novel rhodamine-based colorimetric and fluorescent sensor for the dual-channel detection of Cu and Co/trivalent metal ions and its AIRE activities.

A rhodamine hydrazone 1 bearing coumarin moiety was designed and prepared. Compound 1 exhibited high selectivity toward Co and trivalent metal ions with fluorescence enhancement in CHOH solution. However, 1 selectively responded to Al in nearly pure HO media and was further applied to monitor Al in live cells.

A simple hydrazone as a multianalyte (Cu, Al, Zn) sensor at different pH values and the resultant Al complex as a sensor for F.

A new colorimetric and fluorescence molecular chemosensor based on triazole hydrazone can be used as a multi-probe for selective detection of Al, Zn, and Cu by monitoring changes in the absorption and fluorescence spectral patterns. Results show that Al and Zn ions can induce remarkable fluorescence enhancement at pH 6.0 and pH 10.

A highly sensitive and selective off-on fluorescent chemosensor for hydrazine based on coumarin β-diketone.

A coumarin-based sensor C1, namely 3-acetoacetylcoumarin was designed, synthesized and applied for hydrazine detection. Hydrazinolysis of the chemosensor gives a fluorescent coumarin-pyrazole product C1-NH [3-(3-methyl-1H-pyrazol-5-yl)coumarin], and thus resulting in a prominent fluorescence off-on response toward hydrazine under physiological conditions. The probe is highly selective toward hydrazine over cations, anions and other biologically/environmentally abundant analytes.