Publications by authors named "Xian-Hua Piao"
Article Synopsis
- This study looked at how special immune cells called T regulatory cells (Tregs) affect inflammation in the liver of baby mice born early.
- The researchers injected the mice with a substance called LPS to cause inflammation and observed how Tregs helped control this reaction.
- They found that Tregs were important for keeping the mother's immune system in check so it doesn't harm the developing baby mouse's liver during inflammation.
Objective: To investigate the expression of heme oxygenase-1 (HO-1) and leukemia inhibitory factor (LIF) in maternal plasma and placental tissue in intrauterine infection-induced preterm birth.
Study Design: Using a mouse model of intrauterine infection in preterm birth, we used magnetic beads to extract normal pregnant mouse spleen Treg cells, injecting them into lipopolysaccharide (LPS)-treated pregnant mice. The subjects were divided into 4 groups: control group, LPS group, LPS+PBS group, and LPS+Treg group.