Publications by authors named "Xian Yong Gui"
Objectives: To define endoscopic and histological remission in ulcerative colitis (UC) accurately, several scoring systems have been established. A novel virtual electronic chromoendoscopy score, the Paddington International Virtual ChromoendoScopy ScOre (PICaSSO), was developed, validated, and reproduced to assess inflammation grade and predict patient prognosis. We externally verified and validated the clinical value of PICaSSO in UC patients.
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- - The study investigates colorectal cancer (CRC) in patients with inflammatory bowel disease (IBD) in China and Canada, comparing clinical and pathological characteristics from 78 patients over 13 years.
- - Results show that the Beijing group had a higher percentage of ulcerative colitis (UC), younger average age at CRC diagnosis, and fewer mucinous adenocarcinomas compared to the Calgary group.
- - Despite these differences, both groups exhibited similar features of IBD-CRC such as prolonged colitis duration, active inflammation, and advanced cancer stages, highlighting some shared risks and characteristics between populations.
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignant tumor. Acinar-to-ductal metaplasia (ADM) and pancreatic intraepithelial neoplasia (PanIN) are both precursor lesions that lead to the development of PDAC. Reg family proteins (Reg1A, 1B, 3A/G, 4) are a group of calcium-dependent lectins that promote islet growth in response to inflammation and/or injuries.
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