Publications by authors named "Xian Jun Jin"
(L.) DC (Compositae) (GD) could be found in various parts of Asia. It has been used as a traditional medicine to treat diabetes, high blood pressure, and other diseases, but its effects have not yet been scientifically confirmed.
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- The study investigated the effects of Hwangryunhaedoktang (HHT), a herbal compound, on inflammation caused by lipopolysaccharides (LPS) in macrophage cells called RAW264.7.
- Results showed that HHT reduced nitric oxide production and the expression of inflammatory markers in a dose-dependent manner, while inhibiting key signaling pathways, including NF-κB and MAPKs, associated with inflammation.
- The findings suggest that HHT could have potential therapeutic benefits for managing inflammation by decreasing the secretion of pro-inflammatory cytokines like TNF-α and IL-6.
A CuI-catalyzed tandem reaction of 5-(2-bromoaryl)-N-aryl-1H-pyrazol-3-amines with active acetonitrile derivatives to prepare pyrazolo[5,1-a]isoquinolines in good to excellent yields has been successfully developed under mild conditions with heterocyclic ketene aminals (HKAs) as new ligands. This is the first time HKAs have been used as ligands for copper-catalyzed coupling reactions.
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