Chemical composition determination and transcriptomic analyses provide insight into the differences between wild and grafted Semen Ziziphi Spinosae.

Semen Ziziphi Spinosae (SZS) is a traditional Chinese herbal medicine widely used to treat insomnia and anxiety in clinical practice. Currently, the demand for SZS is increasing every year, but the production of wild SZS is unstable due to environmental factors. Grafting sour jujube scions onto sour jujube or jujube tree stocks can achieve a high production rate within a short period of time.

Spatial distribution of metabolites in processing Ziziphi Spinosae Semen as revealed by matrix-assisted laser desorption/ionization mass spectrometry imaging.

Ziziphi Spinosae Semen (ZSS) is the first choice for the treatment of insomnia. This research aimed to reveal the spatial distribution of identifying quality markers of ZSS and to illustrate the metabolite quality characteristics of this herbal medicine. Here, we performed a matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) in situ to detect and image 33 metabolites in ZSS, including three saponins, six flavonoids, four alkaloids, eight fatty acids, and 12 amino acids.

Integrated metabolomics and transcriptomics analysis reveals γ-aminobutyric acid enhances the ozone tolerance of wheat by accumulation of flavonoids.

Wheat is susceptible to atmospheric ozone (O) pollution, thus the increasing O is a serious threat to wheat production. γ-aminobutyric acid (GABA) is found to play key roles in the tolerance of plants to stress. However, few studies elaborated the function of GABA in response of wheat to O.

Identification of potentially suitable areas for nucleosides of Pinellia Ternata (Thunb.) Breit using ecological niche modeling.

Pinellia ternata, a traditional Chinese medicine, is well-renowned for its effectiveness in treating sickness such as coughs with excessive phlegm, vomiting, and nausea. The nucleoside components of P. ternata have been shown to have antitumor activity.

Responses of soil nutrients and rhizosphere microbial communities of a medicinal plant to vermicompost.

Vermicomposting is an important strategy for restoring soil function and fertility. However, information on the effects of vermicompost application in intensive planting systems has rarely been reported. Here, we focus on the effects of different vermicompost levels and chemical fertilizer (CF) strategies on soil chemical properties, soil enzymes, and soil rhizosphere microbial communities (bacteria and fungi) in a field experiment.

Phytochemical profile and biological activities of the essential oils in the aerial part and root of Saposhnikovia divaricata.

The dried root of Saposhnikovia divaricata (Turcz.) Schischk. is popular as a good medicinal material, however the abundant aerial part is often discarded, which caused the waste of resources.

Predictive Analysis of Quality Markers of Atractylodis Rhizoma Based on Fingerprint and Network Pharmacology.

Background: Atractylodes chinensis (DC.) Koidz. (A.

Essential oil from leaves: A promising green control agent against sp.

is a woody plant with important ecological functions in different regions of China, but its essential oils (EO) against plant pathogenic fungi remain largely undetermined. The purpose of our study was to assess the chemical composition and antifungal activity of . EO based on optimization of the extraction process.

Elevated ozone decreases the multifunctionality of belowground ecosystems.

Elevated tropospheric ozone (O ) affects the allocation of biomass aboveground and belowground and influences terrestrial ecosystem functions. However, how belowground functions respond to elevated O concentrations ([O ]) remains unclear at the global scale. Here, we conducted a detailed synthesis of belowground functioning responses to elevated [O ] by performing a meta-analysis of 2395 paired observations from 222 publications.

[Chemical pattern recognition of Atractylodes chinensis from different producing areas and establishment of quantitative analysis of multi-components by single marker (QAMS) method for four components].

This study established the fingerprint and combined it with chemical pattern recognition to evaluate the quality of Atractylodes chinensis samples from different producing areas and then employed the quantitative analysis of multi-components by single marker(QAMS) method to verify the feasibility and applicability of the established method in the quality evaluation of A. chinensis. The fingerprints of A.

To study the mechanism of Scutellariae Radix and Astragaloside in the treatment of lung cancer based on network pharmacology.

The aim of the study wasto explore the target and potential mechanism of Scutellariae Radix and Astragaloside in the treatment of lung cancer infection by network pharmacology. The target information of baicalein and flavonin was mined from CTD database and Swiss database. Genecards database, DRUGBANK database, and OMIM database were used to search for lung cancer related genes.

Differences in gene expression and endophytic bacterial diversity in Koidz. rhizomes from different growth years.

Koidz. (AMK) is widely used in traditional Chinese medicine owing to its pharmacological activity. Here, we aimed to characterize the differentially expressed genes (DEGs) of one- and three-year growth (OYG and TYG) rhizomes of AMK, combined with endophytic bacterial diversity analysis using high-throughput RNA sequencing.

Astragaloside IV and Saponins of Rhizoma Polygonati Cure Cyclophosphamide-Induced Myelosuppression in Lung Adenocarcinoma Down-Regulating miR-142-3p.

Our previous study revealed that Shuanghuang Shengbai granule could cure the myelosuppression induced by cyclophosphamide (CTX) in lung cancer. However, its hematopoietic effects and molecular mechanisms remain not fully understood. Therefore, this study was intended to investigate the effects and the underlying mechanisms of Astragaloside IV (AS) and saponins of rhizoma polygonati (SRP), the two main bioactive ingredients of Shuanghuang Shengbai granule, on CTX-induced myelosuppression.

Assessing the effects of elevated ozone on physiology, growth, yield and quality of soybean in the past 40 years: A meta-analysis.

Soybean (Glycine max) production is seriously threatened by ground-level ozone (O) pollution. The goal of our study is to summarize the impacts of O on physiology, growth, yield, and quality of soybean, as well as root parameters. We performed meta-analysis on the collated 48 peer-reviewed papers published between 1980 and 2019 to quantitatively summarize the response of soybean to elevated O concentrations ([O]).

Using organic fertilizers to increase crop yield, economic growth, and soil quality in a temperate farmland.

We used a constant total N application base rate to conduct a two-year field experiment comparing the effects of three organic fertilizers (rapeseed meal (RSM), soybean meal (SBM), and cattle manure (CM)) on the crop yield, economic growth, and soil quality of a winter wheat-summer maize rotation system. Winter wheat and summer maize in rapeseed meal treatment (RSMT), soybean meal treatment (SBMT), and cattle manure treatment (CMT) showed yield increases of 161%, 299%, and 256%, respectively, when compared to no organic fertilizer treatment (CK) ( < 0.05).

Two-stage randomized trial design for testing treatment, preference, and self-selection effects for count outcomes.

While the traditional clinical trial design lays emphasis on testing the treatment effect between randomly assigned groups, it ignores the role of patient preference for a particular treatment in the trial. Yet, for healthcare providers who seek to optimize the patient-centered treatment strategy, the evaluation of a patient's psychology toward each treatment could be a key consideration. The two-stage randomized trial design allows researchers to test patient's preference and selection effects, in addition to the treatment effect.

Responses of weed community, soil nutrients, and microbes to different weed management practices in a fallow field in Northern China.

The long-term use of herbicides to remove weeds in fallow croplands can impair soil biodiversity, affect the quality of agricultural products, and threaten human health. Consequently, the identification of methods that can effectively limit the weed seed bank and maintain fallow soil fertility without causing soil pollution for the next planting is a critical task. In this study, four weeding treatments were established based on different degrees of disturbance to the topsoil: natural fallow (N), physical clearance (C), deep tillage (D), and sprayed herbicide (H).

Utilization of addiction treatment among U.S. adults with history of incarceration and substance use disorders.

Background: The high prevalence of substance use disorders (SUDs) among incarcerated adults in the U.S. is well-known, but there has been less examination of SUD treatment and rates of incarceration among the population of adults with SUDs as the denominator.

Comparisons of weed community, soil health and economic performance between wheat-maize and garlic-soybean rotation systems under different weed managements.

This study compared the impacts of different weed managements on weed community, soil health and economic performance between the wheat-maize (WM) and garlic-soybean (GS) rotations. A total of four treatments (HT, tillage without herbicide; HT, without both herbicide and tillage; HT, both herbicide and tillage; HT, herbicide without tillage) were designed for both rotations. A total of 16 weed species were recorded in the WM rotation, with life forms of 62% for annuals, 12% for annual + perennial and 20% for perennials.

Nitric oxide alleviates wheat yield reduction by protecting photosynthetic system from oxidation of ozone pollution.

Accelerated industrialization has been increasing releases of chemical precursors of ozone. Ozone concentration has risen nowadays, and it's predicted that this trend will continue in the next few decades. The yield of many ozone-sensitive crops suffers seriously from ozone pollution, and there are abundant reports exploring the damage mechanisms of ozone to these crops, such as winter wheat.

Large reductions in pesticides made possible by use of an insect-trapping lamp: a case study in a winter wheat-summer maize rotation system.

Background: Increasing attention is being paid to physical methods to control pests such as insect trapping. In order to examine how pesticides can reasonably be combined with the use of an insect-trapping lamp and by how much this can reduce the amount of pesticide used, five treatments were applied to a winter wheat-summer maize rotation system in eastern China: a treatment in which only pesticides were used; a treatment with only insect-trapping lamps; insect-trapping lamps plus one application of pesticides; insect-trapping lamps plus two applications of pesticides; insect-trapping lamps plus three applications of pesticides.

Results: The results showed that, when pesticides were reduced by 25-35%, the insect-trapping lamps controlled the insect population well and yields were not decreased but were actually increased, with pesticides being applied only at 2 days before winter wheat planting, at winter wheat flowering and at the big flare stage of summer maize.