Publications by authors named "Xian Chong Zhou"
Article Synopsis
- The study aimed to assess the effectiveness of a clinical decision support system (CDSS) that uses a weight loss prediction model for patients undergoing radiotherapy.
- A predictive model was developed using data from 63 patients, achieving good accuracy, and then tested on 100 patients by four physicians with varying experience levels, both with and without the CDSS.
- Results showed that the CDSS significantly improved physicians' accuracy in identifying patients at risk of significant weight loss, particularly for those with less experience.
Article Synopsis
- The study investigates the neutrophil-to-lymphocyte ratio (NLR) as a prognostic marker in patients with head and neck squamous cell carcinoma (HNSCC), finding higher NLR correlates with poor outcomes.
- The analysis involved 123 patients using statistical methods to evaluate the relationship between NLR and survival rates post-chemoradiotherapy.
- Results indicate that while NLR is associated with both recurrence-free and overall survival, it loses independent prognostic value when considering the positive influence of HPV status, suggesting HPV may play a critical role in patient prognosis.
Reduction of Pharyngocutaneous Fistulae in Laryngectomy Patients by a Comprehensive Performance Improvement Intervention.
Otolaryngol Head Neck Surg
December 2015
Objective: Pharyngocutaneous fistula is a common complication in laryngectomy patients, particularly in previously irradiated cases. We initiated a comprehensive performance improvement intervention in all head and neck surgery patients intended to reduce postoperative infection and fistulae rates. We report our review of outcomes within laryngectomy patients.
View Article and Find Full Text PDFThe majority of patients with curative resection of pancreatic ductal adenocarcinoma recur within 5 years of resection. However, the prognosis associated with different patterns of recurrence has not been well studied. A retrospective review of patients who underwent curative surgical resection of pancreatic cancer was performed.
View Article and Find Full Text PDFBackground: Securing negative surgical margins is a critical goal for head and neck surgery. Local recurrence develops even in some patients who have histologically negative surgical margins. Minimal residual tumor cells may lead to locoregional recurrence despite clear histologic margins reported at the time of resection of head and neck squamous cell carcinoma (HNSCC).
View Article and Find Full Text PDFPurpose: Promoter hypermethylation has been recently proposed as a means for head and neck squamous cell carcinoma (HNSCC) detection in salivary rinses. In a prospective study of a high-risk population, we showed that endothelin receptor type B (EDNRB) promoter methylation in salivary rinses is a useful biomarker for oral cancer and premalignancy.
Experimental Design: Using that cohort, we evaluated EDNRB methylation status and 8 additional genes.