ZNF281 inhibits mitochondrial biogenesis to facilitate metastasis of hepatocellular carcinoma.

Zinc finger protein 281 (ZNF281) has been shown to promote tumor progression. However, the underlying mechanism remains to be further elucidated. In this study, ZNF281 knockdown increased the expression of mitochondrial transcription factor A (TFAM) in hepatocellular carcinoma (HCC) cells, accompanied with increment of mitochondrial content, oxygen consumption rate (OCR) and levels of TCA cycle intermetabolites.

Inhibition of Annexin A10 Contributes to ZNF281 Mediated Aggressiveness of Hepatocellular Carcinoma.

Objective: To investigate the involvement and transcriptional targets of zinc finger protein 281 (ZNF281) in the progression of hepatocellular carcinoma (HCC).

Methods: The expression of ZNF281 in HCC was detected in tissue microarray and cell lines. The role of ZNF281 in aggressiveness of HCC was examined using wound healing, matrigel transwell, pulmonary metastasis model and assays for expression of EMT markers.

Status and influencing factors of patients with kinesiophobia after insertion of peripherally inserted central catheter: A cross-sectional study.

This study aimed to investigate the current status and influencing factors of kinesiophobia in patients after insertion of peripherally inserted central catheter (PICC). A total of 240 patients with PICC were included. Their postinsertion status and influencing factors were investigated using the general information questionnaire, Tampa Scale of Kinesiophobia (TSK), Medical Coping Modes Questionnaire, Numerical Rating Scale, and Self-rating Anxiety Scale.

Enhanced photocatalytic degradation of gaseous toluene and liquidus tetracycline by anatase/rutile titanium dioxide with heterophase junction derived from materials of Institut Lavoisier-125(Ti): Degradation pathway and mechanism studies.

Anatase/rutile titanium dioxide (TiO) with heterophase junction and large Brunauer-Emmett-Teller (BET) specific surface area (50.1 m g) is successfully synthesized by calcinating Materials of Institut Lavoisier-125(Ti) (MIL-125(Ti)) with 30% O/Ar at the temperature of 600 °C (M-O-600). Several techniques are used to examine the physicochemical, photoelectrochemical and optical properties of samples, and their photocatalytic performances are evaluated by photodegradation of gaseous toluene and liquidus tetracycline (TC) under visible light illumination.

A facile synthesis for uniform tablet-like TiO/C derived from Materials of Institut Lavoisier-125(Ti) (MIL-125(Ti)) and their enhanced visible light-driven photodegradation of tetracycline.

The uniform tablet-like TiO/C nanocomposites with two crystal types (rutile and anatase) and large specific surface area (438 m g) were successfully prepared by Materials of Institut Lavoisier-125(Ti) (MIL-125(Ti)) calcined at a suitable temperature and applied for photocatalytic tetracycline (TC). The nanocomposites were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM) and mapping, N adsorption-desorption isotherms, photoluminescence spectra (PL), photocurrent, and X-ray photoelectron spectroscopy (XPS). The changes of physicochemical parameters are discussed in detail.