The digital transformation of nursing practice: an analysis of advanced IoT technologies and smart nursing systems.

Facing unprecedented challenges due to global population aging and the prevalence of chronic diseases, the healthcare sector is increasingly relying on innovative solutions. Internet of Things (IoT) technology, by integrating sensing, network communication, data processing, and security technologies, offers promising approaches to address issues such as nursing personnel shortages and rising healthcare costs. This paper reviews the current state of IoT applications in healthcare, including key technologies, frameworks for smart nursing platforms, and case studies.

Exosomal circHIF1A derived from hypoxic-induced carcinoma-associated fibroblasts promotes hepatocellular carcinoma cell malignant phenotypes and immune escape.

Hypoxia is a hallmark of solid tumors. Cancer-associated fibroblasts (CAFs) are an important component of the tumor microenvironment, and CAF-derived exosomes are involved in cancer genesis and progression. Here, this work investigated the role and mechanism of exosomal circHIF1A derived from hypoxia-induced CAFs in hepatocellular carcinoma (HCC) tumorigenesis.

Extrahepatic bile duct reconstruction in pigs with heterogenous animal-derived artificial bile ducts: A preliminary experience.

Background: Extrahepatic biliary duct injury (BDI) remains a complicated issue for surgeons. Although several approaches have been explored to address this problem, the high incidence of complications affects postoperative recovery. As a nonimmunogenic scaffold, an animal-derived artificial bile duct (ada-BD) could replace the defect, providing good physiological conditions for the regeneration of autologous bile duct structures without changing the original anatomical and physiologic conditions.