Non-Targeted Metabolomics Analysis of Mother and Infant in Gestational Diabetes Mellitus and Neonatal Clinical Characterization.

Background: The goal was to analyze serums of GDM patients and healthy pregnant women using HPLC-MS and preliminarily screen differential metabolites by metabolomics.

Method: Sixty pregnant women who underwent elective cesarean section at term in Dongguan Dalang Hospital from January 2023 to April 2023 were selected and divided into the GDM group and healthy pregnancy group. Pre-pregnancy and pregnancy examination information, such as age, BMI, OGTT results, triglyceride, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and other clinical data were col-lected for statistical analysis.

Efficacy and Adverse Effects of Atrasentan in Patients with Diabetic Nephropathy: A Meta-Analysis.

Background: About 30% of Type 1 diabetes (T1DM) patients and 40% of Type 2 diabetes (T2DM) patients were diagnosed with diabetic nephropathy, which has also greatly affected the global end-stage renal disease (ESRD) outcome. Atrasentan is a selective endothelin receptor type A (ETA) antagonist initially studied for the potential treatment of cancer. However, the role of Atrasentan was not sure in the DM.

A case of Gitelman syndrome with membranous nephropathy.

Background: Gitelman syndrome (GS) is a rare autosomal recessive inherited salt-losing tubulopathy (SLT). Here, we report, for the first time, a case of GS overlapping nephrotic syndrome (NS) related to PLA2R-associated membranous nephropathy (MN).

Case Presentation: We described a male patient had a 4-year history of recurrent fatigue.

Graphene-doped electrochemical copolymer coating of 2,2-bithiophene and 3-methylthiophene for the highly effective solid-phase microextraction of volatile benzene homologues.

We report the electrochemical fabrication of a poly(2,2-bithiophene-co-3-methylthiophene)-graphene composite coating and its application in the headspace solid-phase microextraction and gas chromatography determination of benzenes (i.e., bromobenzene, 4-bromotoluene, 2-nitrotoluene, 3-nitrotoluene and 1,2,4-trichlorobenzene).

A Poly(ethylenglycol) Functionalized ZIF-8 Membrane Prepared by Coordination-Based Post-Synthetic Strategy for the Enhanced Adsorption of Phenolic Endocrine Disruptors from Water.

Metal-organic framework (MOF) membranes have received increasing attention as adsorbents, yet single phase MOF membranes have certain limitations, which frustrate their capacity performance. In this work a MOF composite membrane was successfully prepared by a facile and green strategy through reasonable design. At first, a defect-free ZIF-8 membrane was fabricated on an ionic liquid modified pencil bar by a solvothermal method.

Electrochemical preparation of poly(3-methylthiophene-carbazole)/graphene oxide composite coating for the highly effective solid-phase microextraction of some fragrance.

A poly(3-methylthiophene-carbazole)/graphene oxide composite coating was prepared on a stainless steel wire through electrochemical method. It showed high extraction efficiency, thermal stability and durability than those of corresponding single-component coatings due to the synergistic effect of different components. The resulting fiber was used for the headspace solid phase microextraction of octanal, nonanal, decanal, undecanol and dodecanol, followed by gas chromatography detection.