Publications by authors named "Xiadong Ju"
Use of Human Placenta-Derived Cells in a Preclinical Model of Tendon Injury.
J Bone Joint Surg Am
July 2019
Article Synopsis
- Emerging data indicates that human cells from extraembryonic tissues, like the placenta, may be effective in repairing musculoskeletal injuries, particularly in tendon healing.
- In a study with male rats, the injection of placental expanded cells (PLX-PAD) after collagenase-induced tendon damage resulted in significantly improved tendon strength after 2 weeks compared to controls given saline.
- Although the PLX-PAD treatment showed a temporary increase in tendon load capacity and an early inflammatory response, there were no significant long-term differences in tendon stiffness or collagen organization by the end of the study.