Publications by authors named "Xiading Zhang"
Article Synopsis
- Hepatocellular carcinoma (HCC) is a significant global health issue with few treatment options and a poor survival rate, prompting research into its underlying mechanisms.
- This study focuses on the role of the chemokine CCL28 in promoting HCC progression and its potential as a new therapeutic target.
- Results indicate that higher levels of CCL28 are directly linked to worse HCC outcomes, enhancing cancer cell proliferation, migration, and invasion through specific signaling pathways.
Article Synopsis
- Exosomes play a crucial role in the progression of hepatocellular carcinoma (HCC) and are being explored as potential targets for diagnosis and therapy.
- Three datasets were analyzed to identify differentially expressed genes (DEGs) related to HCC, leading to the discovery of a hub gene, FTCD, which showed a protective effect and was linked to macrophage behavior in HCC.
- FTCD has potential as a biomarker for HCC, indicating the need for further research into its interactions with immune cells during cancer progression.
Emerging evidence has indicated that mesenchymal stem cells (MSCs) are involved in the modulation of inflammation. Human placenta-derived (HPL)-MSCs exist in sufficient quantities and play a role in immune regulation. However, the exact roles of HPL-MSCs in inflammation and the specific underlying mechanisms are not well defined.
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