Publications by authors named "Xia-Bing Fu"
Article Synopsis
- Two new Cu(II)-dipeptide complexes, [Cu(Gly-Gly)(TBZ)(Cl)]·4H2O and [Cu(Gly-l-Leu)(TBZ)(Cl)]·H2O, were synthesized and characterized using various analytical techniques, highlighting their distinctive chemical properties.
- The complexes demonstrated significant binding to calf thymus DNA and effectively cleaved pBR322 DNA with the help of ascorbic acid, suggesting an oxidative damage mechanism.
- In cytotoxicity assays, the complexes exhibited notable effectiveness against human carcinoma cell lines, especially HeLa cells, indicating their potential as novel chemotherapeutic agents.
Two new water-soluble copper(ii)-dipeptide complexes: [Cu(glygly)(PyTA)]ClO4·1.5H2O (1) and [Cu(glygly)(PzTA)]ClO4·1.5H2O (2) (glygly = glycylglycine anion, PyTA = 2,4-diamino-6-(2'-pyridyl)-1,3,5-triazine and PzTA = 2,4-diamino-6-(2'-pyrazino)-1,3,5-triazine), utilizing two interrelated DNA base-like ligands (PyTA and PzTA), have been synthesized and characterized.
View Article and Find Full Text PDFA new ternary copper(II)-dipeptide complex [Cu(glygly)(HPB)(Cl)]⋅2H2O (glygly=glycylglycine anion, HPB=2-(2'-pyridyl)benzimidazole) has been synthesized and characterized. The DNA interaction of the complex was studied by spectroscopic methods, viscosity, and electrophoresis measurements. The antioxidant activity was also investigated using the pyrogallol autoxidation assay.
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