Non-invasive neuromodulation treatment for depression in adolescents: A systematic review and meta-analysis.

Background: Synthesized evidence regarding the effectiveness of non-invasive neuromodulation treatment for adolescents remains scarce. This study aimed to perform the first meta-analysis of the impact of neuromodulation treatment on depressive symptoms in adolescents.

Methods: According to the PRISMA guidelines, a comprehensive review covering databases in English and Chinese from their inception to November 30, 2023, was conducted.

Dust mite antigens endow dendritic cells with the capacity to induce a Th2 response by regulating their methylation profiles.

Background: It is well-known that Dendritic cells (DCs) are essential in the development of airway Th2 polarization and airway allergy (AA). The underlying mechanism is still not fully understood. The objective of this study is to examine the role of methyltransferase-like protein-5 (Mettl5), a methyltransferase involved in N6-methyladenosine (m6A) methylation, in altering DC's properties to facilitate the development of Th2 polarization and AA.

Free vibration of nanobeams with surface and dynamic flexoelectric effects.

In this paper, the free vibration of piezoelectric nanobeams considering static flexoelectric, dynamic flexoelectric, and surface effects is studied. Based on the theories of the Timoshenko beam and Euler-Bernoulli beam, a theoretical model of flexoelectric nanobeams is established and the governing equations and boundary conditions of this model are derived using the variational principle. Then, the analytical solution of the frequency equation is obtained by using the Navier method.

Spectral Flux Enhancement of X Rays for Addressing Ultranarrow Nuclear Transitions.

Recently, the 1.4 feV ultranarrow nuclear transition at 12.4 keV energy in ^{45}Sc was resonantly excited for the first time using radiation from the self-seeded EuXFEL laser [Y.

Copper pyrazole addition regulates soil mineral nitrogen turnover by mediating microbial traits.

The huge amount of urea applied has necessitated best-developed practices to slow down the release of nitrogen (N) fertilizer while minimizing nitrate loss. However, the impact of nitrification inhibitors on mineral-N turnover and the associated microbial mechanisms at different stages remains unknown. A 60-day incubation experiment was conducted with four treatments: no fertilizer (CK), urea (U), urea with copper pyrazole (UC), and urea coated with copper pyrazole (SUC), to evaluate the changes about soil ammonia N ( -N) and nitrate N ( -N) levels as well as in soil microbial community throughout the whole incubation period.

Effects of Dietary Ursolic Acid on Growth Performance and Intestinal Health of Largemouth Bass ().

This study aimed to investigate the effects of ursolic acid (UA) on the growth performance and intestinal health of largemouth bass (). Four diets were formulated with UA supplementation at 0, 250, 500, and 1000 mg/kg, defined as the control (CON), UA250, UA500, and UA1000, respectively. After an 8-week feeding experiment, the results showed that, in the UA500 group, the final body weight (FBW), weight gain rate (WGR), and specific growth rate (SGR) increased, and the feed conversion ratio (FCR) and hepatosomatic index decreased.

A Bibliometric Analysis of Metabolic Reprogramming in the Tumor Microenvironment From 2003 to 2022.

Background: Despite considerable progress in cancer immunotherapy, it is not available for many patients. Resistance to immune checkpoint blockers arises from the intricate interactions between cancer and its microenvironment. Metabolic reprogramming in tumor and immune cells in the tumor microenvironment (TME) influences anti-tumor immune responses by remodeling the immune microenvironment.

A Sheep Identification Method Based on Three-Dimensional Sheep Face Reconstruction and Feature Point Matching.

As the sheep industry rapidly moves towards modernization, digitization, and intelligence, there is a need to build breeding farms integrated with big data. By collecting individual information on sheep, precision breeding can be conducted to improve breeding efficiency, reduce costs, and promote healthy breeding practices. In this context, the accurate identification of individual sheep is essential for establishing digitized sheep farms and precision animal husbandry.

Nuclear quantum memory for hard x-ray photon wave packets.

Optical quantum memories are key elements in modern quantum technologies to reliably store and retrieve quantum information. At present, they are conceptually limited to the optical wavelength regime. Recent advancements in x-ray quantum optics render an extension of optical quantum memory protocols to ultrashort wavelengths possible, thereby establishing quantum photonics at x-ray energies.

A fluid-structure interaction simulation on the impact of transcatheter micro ventricular assist devices on aortic valves.

Background And Objective: The implantation of ventricular assist devices (VADs) has become an important treatment option for patients with heart failure. Aortic valve insufficiency is a common complication caused by VADs implantation. Currently, there is very little quantitative research on the effects of transcatheter micro VADs or the intervention pumps on the aortic valves.

Nemo mRNA vaccination improves airway barrier function in mice with airway allergy.

Epithelial barrier dysfunction plays an important role in the pathogenesis of Th2 bias. The mechanism requires further clarification. NEMO is associated with regulating apoptotic activities in the cell.

Endothelial cell-derived extracellular vesicles modulate the therapeutic efficacy of mesenchymal stem cells through IDH2/TET pathway in ARDS.

Background: Acute respiratory distress syndrome (ARDS) is a severe and fatal disease. Although mesenchymal stem cell (MSC)-based therapy has shown remarkable efficacy in treating ARDS in animal experiments, clinical outcomes have been unsatisfactory, which may be attributed to the influence of the lung microenvironment during MSC administration. Extracellular vesicles (EVs) derived from endothelial cells (EC-EVs) are important components of the lung microenvironment and play a crucial role in ARDS.

Treatment with immunosuppressants did not increase the risk of COVID-19 in pemphigus patients: A single-center survey-based study.

Background: The prevalence and outcomes of coronavirus 2019 (COVID-19) among patients using glucocorticoids and immunosuppressants remain controversial.

Aim: The study aims to investigate the impact of immunosuppressants especially glucocorticoids on patients in the Autoimmune Bullous Diseases Cohort of West China Hospital (AIBDWCH) during COVID-19.

Methods: We conducted a cross-sectional survey from December 7, 2022, to February 8, 2023, using questionnaires administered either face-to-face or by phone.

Cu-BTC Derived Mesoporous CuS Nanomaterial as Nanozyme for Colorimetric Detection of Glutathione.

In this paper, Cu-BTC derived mesoporous CuS nanomaterial (m-CuS) was synthesized via a two-step process involving carbonization and sulfidation of Cu-BTC for colorimetric glutathione detection. The Cu-BTC was constructed by 1,3,5-benzenetri-carboxylic acid (HBTC) and Cu ions. The obtained m-CuS showed a large specific surface area (55.

(+)-Catechin ameliorates diabetic nephropathy injury by inhibiting endoplasmic reticulum stress-related NLRP3-mediated inflammation.

Endoplasmic reticulum (ER) stress and chronic sterile inflammation are associated with the pathogenesis of diabetic nephropathy (DN). Catechins are natural polyphenolic compounds found in green tea that possess some health benefits. However, whether (+)-catechin can reduce tubular injury in DN by regulating ER stress and NLRP3-associated inflammation remains uncertain.

A causal association between amyotrophic lateral sclerosis and atrial fibrillation: a two-sample Mendelian randomization study.

Objectives: To look into the connection between amyotrophic lateral sclerosis (ALS) and atrial fibrillation (AF) using Mendelian randomization (MR).

Methods: Two-sample MR was performed using genetic information from genome-wide association studies (GWAS). Genetic variants robustly associated with ALS and AF were used as instrumental variables.

Does settlement land expansion necessarily induce the decrease of cultivated land? Differences in national scale and local counties of China.

With the extensive industrialization and urbanization taking place in China during the recent decades, land use throughout the country has experienced profound changes influenced not only by the demand for population growth and living standard improvement but also by the constraints of series of land use policies. However, whether the conflict between the expansion of settlement land (SL) and the loss of cultivated land (CL) have been resolved at the national scale or transferred between the local regions remains unclear. Based on yearly ESA CCI land use and land cover products from 1992 to 2020, the long-term trends of quantity and spatial pattern of SL expansion and CL change in China from national and local views were investigated using trend statistic methods, and finally a comprehensive zoning framework was proposed to recognize the trade-off and synergies relationships between SL expansion and CL change.

Dual effects on vegetation from urban expansion in the drylands of northern China: A multiscale investigation using the vegetation disturbance index.

Drylands contribute roughly 40 % of the global net primary productivity and are essential for achieving sustainable development. Investigating the effects on vegetation from urban expansion in drylands within the context of rapid urbanization could help enhance the sustainability of dryland cities. With the use of the drylands of northern China (DNC) as an example, we applied the vegetation disturbance index to investigate the negative and positive effects on vegetation from urban expansion in drylands.

Astragaloside IV attenuates renal tubule injury in DKD rats via suppression of CD36-mediated NLRP3 inflammasome activation.

Background: In recent years, diabetic kidney disease (DKD) has emerged as a prominent factor contributing to end-stage renal disease. Tubulointerstitial inflammation and lipid accumulation have been identified as key factors in the development of DKD. Earlier research indicated that Astragaloside IV (AS-IV) reduces inflammation and oxidative stress, controls lipid accumulation, and provides protection to the kidneys.