Association between IL-27 2905T/G genotypes and the risk and survival of cervical cancer: a case-control study.

Background: Interleukin-27 (IL-27) has been recognized as a pleiotropic cytokine with both pro- and anti-inflammatory properties.

Patients And Methods: A case-control study was conducted to investigate the possible associations of IL-27 gene polymorphisms with susceptibility to cervical cancer and clinical outcome.

Results: Our results suggested that the IL-27 2905T/G was significantly associated with a decreased risk of cervical cancer.

Associations between Fas/FasL polymorphisms and susceptibility to cervical cancer: a meta-analysis.

Unlabelled: Genetic polymorphisms in the Fas/Fas ligand (FasL) gene were proposed to be associated with susceptibility to cervical cancer, but previous studies reported controversial findings. We performed a meta-analysis to assess the associations between Fas/FasL polymorphisms and susceptibility to cervical cancer. We carried out a literature search in PubMed and Embase databases for studies on the associations between Fas/FasL polymorphisms and susceptibility to cervical cancer.