Excess genistein suppresses the synthesis of extracellular matrix in female rat mandibular condylar cartilage.

Aim: To investigate the effect of excess genistein on the extracellular matrix in mandibular condylar cartilage of female rats in vivo.

Methods: Female SD rats were administered through oral gavage with genistein (50 mg/kg) or placebo daily for 6 weeks. The morphological changes of temporomandibular joints were studied with HE staining.

Dose-dependent effects of genistein on bone homeostasis in rats' mandibular subchondral bone.

Aim: To investigate the effect of genistein on bone homeostasis in mandibular subchondral bone of rats.

Methods: Female SD rats were administered with genistein (10 and 50 mg/kg) or placebo by oral gavage for 6 weeks. Then the animals were sacrificed, and histomorphology and micro-structure of mandibular condyle were examined using HE staining and micro-CT analysis, respectively.

Root canal morphology of permanent maxillary teeth in the Han nationality in Chinese Guanzhong area: a new modified root canal staining technique.

Introduction: The purpose of this study was to investigate the canal morphology of 504 maxillary permanent teeth of subjects of Han nationality in Chinese Guanzhong area.

Methods: Maxillary permanent teeth were randomly collected in Guanzhong area. After regular preparation, the teeth were immersed into ink without preparing access cavities and then put into hyperbaric oxygen chamber (0.