Publications by authors named "Xi-cui Zong"

Antibacterial peptides (ABPs) with cancer-selective toxicity have received much more attention as alternative chemotherapeutic agents in recent years. However, the basis of their anticancer activity remains unclear. The modification of cell surface glycosylation is a characteristic of cancer cells.

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TNFSF13 is one of the tumor necrosis factor (TNF) superfamily members that plays important roles in immune homeostasis and proliferation or apoptosis of certain tumor cell lines. This report describes the development of Xenopus laevis TNFSF13 as a model to study its important role in relation to immunological diseases. In brief, TNFSF13 from Xenopus laevis (designated XlTNFSF13) was first amplified by RT-PCR and rapid amplification of cDNA end (RACE) techniques.

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Synopsis of recent research by authors named "Xi-cui Zong"

  • - Xi-cui Zong's research emphasizes the exploration of antibacterial peptides (ABPs) as potential alternative therapies for breast cancer, focusing on their cancer-selective toxicity and the role of glycosylation in their anticancer activity.
  • - The study on TNFSF13 (APRIL) in Xenopus laevis aims to establish this frog species as a novel model for investigating immunological diseases, highlighting the cytokine's significance in immune regulation and tumor cell dynamics.
  • - Zong's work combines molecular cloning, bioinformatics, and biological activity assessments to enhance understanding of peptide roles in cancer and immune response, contributing to the broader field of biochemistry and pharmacology research.