Publications by authors named "Xi-Yue Liu"
Article Synopsis
- The corticospinal tract (CST) is crucial for voluntary movement in vertebrates, and Netrin-1 serves as a key guidance molecule for axons crossing the midline during embryonic development.
- Research using conditional knockout (CKO) mice revealed that the lack of Netrin-1 resulted in CST axons failing to cross over correctly and instead descending on the same side of the spinal cord.
- These findings suggest a significant role of Netrin-1 in CST formation and provide new insights into its involvement in congenital mirror movements (CMM) due to abnormal CST trajectories.
