Isolating Antipathogenic Fungal Coumarins from and Determining Their Primary Mechanism .

Through bioassay-guided isolation, eight undescribed coumarins (-), along with six reported coumarins (-), were obtained from The new structures were determined by using IR, UV, NMR, HRESIMS, and ECD calculations. The results of the biological activity assays showed that compound exhibited broad spectrum antifungal activities against all tested fungi and a significant inhibitory effect on with an EC value of 3.00 μg/mL.