Publications by authors named "Xi-Yan Wei"
Article Synopsis
- Sepsis is a major cause of mortality in severe infections globally, and the study explores how remifentanil, a powerful pain relief drug, affects inflammation in human aortic endothelial cells (HAECs) induced by lipopolysaccharide (LPS).
- The research involved pretreating HAECs with remifentanil or a control solution, followed by stimulation with LPS to analyze inflammation, DNA damage, and specific protein expressions related to inflammation.
- Results showed that remifentanil significantly lowered inflammation markers and DNA damage while impacting key signaling pathways, suggesting it could be a beneficial pain management option for patients with sepsis.
The main objective of this study was to evaluate the potential of quercetin-loaded nanostructured lipid carriers (QT-NLCs) as a topical delivery system. QT-NLCs were prepared by the method of emulsion evaporation-solidification at low temperature. The average entrapment efficiency and drug loading of the optimized QT-NLCs were 89.
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- Scientists wanted to make tiny balls called microspheres that carry a medicine called curcumin to help treat lungs.
- They figured out a way to create these microspheres using special ingredients and a smart method that makes sure they're just right.
- The best microspheres had a smooth surface, held a good amount of curcumin, and can slowly release it over time, which is really useful for helping lungs.
We report a novel alkaline extractable protein of the sperm head that exclusively resides in the post-acrosomal sheath region of the perinuclear theca (PT) and is expressed and assembled in elongating spermatids. It is a protein that shares sequence homology to the N-terminal half of WW domain-binding protein 2, while the C-terminal half is unique and rich in proline. A functional PPXY consensus binding site for group-I WW domain-containing proteins, and numerous unique repeating motifs, YGXPPXG, are identified in the proline-rich region.
View Article and Find Full Text PDF[Preparation and stability investigation of gastrodin dispersible tablets].
Zhong Yao Cai
September 2006
Article Synopsis
- The study focused on preparing and optimizing gastrodin dispersible tablets using an orthogonal design, with disintegration time as a key measure of quality.
- The optimized formulation achieved a disintegration time of 106 seconds by combining two excipients, L-HPC and CMS-Na, resulting in superior dissolution compared to conventional tablets.
- Stability tests confirmed the high quality of the gastrodin dispersible tablets, indicating their effectiveness for use.
Rhodococcus sp. PR-1 with high capability of demulsification on a surfactant-stabilized kerosene-water model emulsion was isolated from sewage of Dagang oil field. It could demulsify the model emulsion completely in 8 hours at 55 degrees C and had better demulsifying capability than chemical demulsifier DGF-01.
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