Repairing cartilage defects using chondrocyte and osteoblast composites developed using a bioreactor.

Background: Articular cartilage injury is a common disease, and the incidence of articular wear, degeneration, trauma and sports injury is increasing, which often lead to disability and reduced quality of life. Unfortunately repair of articular cartilage defects do not always provide satisfactory outcomes.

Methods: Chondrocyte and osteoblast composites were co-cultured using a bioreactor.