Publications by authors named "Xi-Sheng Yang"
Article Synopsis
- A significant percentage of colorectal cancer patients experience liver metastases, contributing to high mortality rates; studies suggest that the intestinal bacteria Fusobacterium nucleatum may play a role in this progression.
- A prospective, double-blind study will involve 300 patients to test if long-term use of the antibiotic metronidazole can reduce the occurrence of liver metastases after surgery.
- The study has received ethics approval and will share its findings through conferences and articles in peer-reviewed journals.
Article Synopsis
- The study compared continuous hand-sewn esophagojejunostomy using barbed suture with mechanical anastomosis during total laparoscopic gastrectomy for treating esophagogastric junction cancer.
- Data from 60 patients (30 in each group) showed that the hand-sewn technique had a significantly shorter anastomosis time and lower operation costs while achieving a longer tumor margin.
- The results suggest that the hand-sewn anastomosis is a practical, safe, and cost-effective method, serving as an effective supplement to mechanical anastomosis without increasing the risk of postoperative complications.
Article Synopsis
- Proximal gastrectomy is becoming popular because it helps preserve stomach function, but it can lead to complications that impact quality of life, prompting the need for better surgical techniques.
- A new study will compare the left-open single-flap technique with the double-flap technique in a multicenter randomized trial involving 250 patients to see which method reduces surgical difficulties and complications.
- The goal is to provide evidence for improving surgical reconstruction methods after proximal gastrectomy, contributing to better clinical practices and guidelines.
Different 18F-FDG imaging: A rare case of liver multiple carcinomas.
Clin Res Hepatol Gastroenterol
January 2023
A 49-year-old man was referred to the hospital with the complaints of haematochezia and weight loss. Colonoscopy and pathological needle biopsy suggested moderately to highly differentiated adenocarcinoma. The patient underwent abdominal CT examination, which demonstrated two augmented and irregular masses in the liver.
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- - The study investigates deep vein thrombosis (DVT) in 1,750 patients with gastric and colorectal cancers, identifying how often it occurs and the associated risk factors, particularly before surgery.
- - Out of the patients reviewed, 73 were found to have DVT, resulting in a prevalence rate of 4.17%, with significant risk factors including being female, stage IV cancer, and higher ASA class.
- - The findings suggest that preoperative venous ultrasonography can effectively detect DVT, helping to prevent postoperative complications like pulmonary thromboembolism (PTE), making it a vital tool in surgical planning for these cancer patients.
Background: Appropriate gastrointestinal reconstruction after proximal gastrectomy can effectively reduce the incidence of postoperative complications in patients with proximal early gastric cancer. However, there is still great controversy about the choice of digestive tract reconstruction after proximal gastrectomy, and there is no clinical consensus on the choice of digestive tract reconstruction after proximal gastrectomy. Currently, there is a lack of large-sample, prospective, randomized controlled studies to compare the efficacy of Kamikawa, double-tract reconstruction, and tube-like stomach reconstruction after proximal gastrectomy.
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- The study focuses on the effectiveness of oral antibiotic bowel preparation (OABP) in reducing anastomotic leakage after elective colorectal cancer surgery, contrasting it with standard practices that do not involve special intestinal preparation.
- The research will enroll 1,500 patients in a multicentre, randomized controlled trial, with participants either receiving antibiotics or undergoing traditional preparation.
- Outcomes will be closely monitored, specifically looking at the occurrence of anastomotic leakage and other severe postoperative events, with ethical approval already granted for the study.
Allograft tolerance is the ultimate goal in the field of transplantation immunology. Immature dendritic cells (imDCs) play an important role in establishing tolerance but have limitations, including potential for maturation, short lifespan in vivo and short storage times in vitro. However, exosomes (generally 30-100 nm) from imDCs (imDex) retain many source cell properties and may overcome these limitations.
View Article and Find Full Text PDFMicroRNAs (miRNAs) are associated with human carcinogenesis and tumor development. Moreover, serum miRNAs can reflect the level of tissue miRNAs and be potential tumor markers. Serum microRNA-21 (miR-21) is overexpressed in many human cancers including hepatocellular carcinoma (HCC).
View Article and Find Full Text PDFHepatocellular carcinoma (HCC) is one of the most common human malignancies and also the leading cause of cancer-related death in the world. The mechanisms underlying the progression and metastasis of HCC remain unclear. The E3 ubiquitin ligase F-box and WD repeat domain-containing 7 (Fbxw7) is broadly considered as a tumor suppressor gene.
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