Zhongguo Shi Yan Xue Ye Xue Za Zhi
April 2018
Objective: To investigate the effect of SH2-containing inositol phosphatase-1 (SHIP-1) on the proliferation, invasion and migration of human leukemia cells as well as phosphatidylinositol-3 kinase (PI3K) / protein kinase B (AKT) signaling pathway.
Methods: The overexpression vector pCDNA3.1-SHIP1 was transfected into THP-1 cells by Lipofectamine 2000.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
June 2017
Objective: To investigate the change of plasma IL-16 level in patients with multiple myeloma(MM) and its clinical significance.
Methods: Sixty-two patients with multiple myeloma were admitted in our hospital from June 2008 to June 2015. Forty healthy volunteers were selected as control group.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
April 2017
Objective: To compare the effects of different dosages of rhG-CSF on duration of aleucocytosis and white blood cell counts after chemotherapy of patients with hematologic malignancies.
Methods: Ninety patients in our hospital from December 2011 to June 2016 were chosen as study objects, and all of them were divided into 3 groups: group A (rhG-CSF 200 µg/m), group B(rhG-CSF 300 µg/m) and group C(rhG-CSF 400 µg/m); 30 patients from January 2004 to January 2007 were chosen as control(control group). The WBC and its duration, WBC and its timepoint were compared among different groups.