[Effect of SHIP-1 on Invasion, Migration and PI3K-AKT Signaling Pathway of Leukemic Cells].

Objective: To investigate the effect of SH2-containing inositol phosphatase-1 (SHIP-1) on the proliferation, invasion and migration of human leukemia cells as well as phosphatidylinositol-3 kinase (PI3K) / protein kinase B (AKT) signaling pathway.

Methods: The overexpression vector pCDNA3.1-SHIP1 was transfected into THP-1 cells by Lipofectamine 2000.

[Change of Plasma Interleukin-16 Level in Patients with Multiple Myeloma and Its Clinical Significance].

Objective: To investigate the change of plasma IL-16 level in patients with multiple myeloma(MM) and its clinical significance.

Methods: Sixty-two patients with multiple myeloma were admitted in our hospital from June 2008 to June 2015. Forty healthy volunteers were selected as control group.

[Effects of Different Dosages of rhG-CSF on Duration of Aleucocytosis and Leukocytes Level after Chemotherapy of Patients with Hematologic Malignancies].

Objective: To compare the effects of different dosages of rhG-CSF on duration of aleucocytosis and white blood cell counts after chemotherapy of patients with hematologic malignancies.

Methods: Ninety patients in our hospital from December 2011 to June 2016 were chosen as study objects, and all of them were divided into 3 groups: group A (rhG-CSF 200 µg/m), group B(rhG-CSF 300 µg/m) and group C(rhG-CSF 400 µg/m); 30 patients from January 2004 to January 2007 were chosen as control(control group). The WBC and its duration, WBC and its timepoint were compared among different groups.